Vet Lines MSDS Nexgard Spectra SDS August 2015 | Page 4

SAFETY DATA SHEET
Product Name: NEXGARD Spectra
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Reviewed on: 26 August 2015
Carcinogenicity: IARC: No ingredient of this product, which is present at levels greater
than or equal to 0.1%, is identified as probable, possible or confirmed
human carcinogen by IARC.
ACGIH: No ingredient of this product, which is present at levels greater
than or equal to 0.1%, is identified as a carcinogen or potential
carcinogen by ACGIH.
NTP: No ingredient of this product, which is present at levels greater
than or equal to 0.1%, is identified as a known or anticipated
carcinogen by NTP.
OSHA: No ingredient of this product, which is present at levels greater
than or equal to 0.1%, is identified as a carcinogen or potential
carcinogen by OSHA.
Reproductive toxicity: No ingredient of this product, which is present at levels greater than or
equal to 0.1%, is identified as a known or anticipated reproductive
toxins.
Teratogencicity/Developmental
Effects No ingredient of this product, which is present at levels greater than or
equal to 0.1%, is identified as a known or anticipated teratogenic or
developmental toxins
SECTION 12: ENVIRONMENTAL INFORMATION
Based upon computer modeling, the LC 50 /EC 50 for afoxolaner
ranged from 0.008 to 1.046 mg/L for freshwater and marine fish,
invertebrates and plants. Based on computer modeling, the
mixture is considered a Category 1 Acute Aquatic Hazard (GHS
standards). However, due to limited quantities (i.e., packaging)
the mixture is not considered an environmental hazard.
Ecotoxicity:
Persistence and degradability: Based upon computer modeling and physico-chemical
characteristics of the ingredients in the mixture, the mixture is
considered biodegradable in the environment.
Bioaccumulative potential: Based on the K ow of the ingredients in the mixture, some of the
ingredients have the potential for bioaccumulation. However,
fugacity modeling and biodegradation testing suggest that the
potential for bioaccumulation of those ingredients is low.
Therefore, it is considered that the mixture will not accumulate
in the environment.
Mobility in soil: Based on the K oc of the ingredients in the mixture and fugacity
modeling, the mixture is not considered to have a high
probability of mobility through the soil.
Results of PBT and vPvB
Assessment: The ingredients in the mixture do not meet the classification
criteria for Persistent, Bioaccumulative and Toxic (PBT)
chemicals, or very Persistent and very Bioaccumulative (vPvB)
chemicals.
SECTION 13: DISPOSAL CONSIDERATIONS
Disposal information :
Dispose of all waste ingredient and containers in accordance with national,
regional, state and local regulations.
SECTION 14: TRANSPORT INFORMATION
Relevant
information: UN3077 ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(Afoxolaner)
Class 9 PG III
Limited quantities: 5kg
Other requirements: N/A