FUTURE HEALTH
3D
TISSUE MODELS
Modelling cell , tissue and organ functions and preclinical device characterisation
RESEARCH GROUP
Existing preclinical in vitro models fall short of accurately mimicking the human body , restricting the refinement of medical devices before they are tested on animals . To address this gap , Professor Megan Lord and her team create sophisticated 3D in vitro tissue models . These models are crafted using a combination of biomaterials , cells , and proteins .
The team has successfully developed prototype 3D in vitro models of blood vessels , designed specifically for evaluating drug and nanoparticle delivery systems . By collaborating with industry partners , these innovative models are being integrated into the development and optimisation of commercial medical devices and therapies .
> Application of Synedgen ' s glycopolymer platform ( US based company ) to the 3D blood vessel model uncovered new applications in drug delivery .
> The 3D blood vessel model supports fundamental research through an Australian Research Council Future Fellowship for Prof Lord ($ 1M ).
Given that many nanomedicines are intended for intravenous administration , this 3D blood vessel model is proving to be of immense value across the industry for testing the efficacy and performance of drugs and nanoparticles .
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