UNSW 100 Innovations Booklet | Page 92

Optical Devices for Neurological Disease Management( Sevren)

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Developing optical neural interfaces to enable high-resolution brainmachine communication and advanced prosthetic control
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Prototype developed
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Challenge
Sevren seeks to develop the next generation of neural interfaces addressing a DARPA challenge of producing an implantable chip that offers up to one million connections to biological tissues( e. g., brain, retina, peripheral nerves). Its successful development would result in life-changing improvements for potential patients.
Solution
The technology allows both the development of scientific instrumentation for neurophysiological studies( e. g., pharmacology) and the creation of novel and disruptive approaches to neural implants. This will allow for the treatment of chronic diseases( e. g., epilepsy), the control of smart prosthesis and the rehabilitation of lost abilities( e. g., vision).
At this early stage, Sevren envisages working with with partners to licence and manufacture its first series of products in the scientific instrumentation segment.
Target customers / end-users
• short term: scientific instrumentation segment
• long term: implantable neural interfaces segment.
Progress
• secured a broad portfolio of IP from UNSW covering the conceptual approach and fabrication
• publication in high-impact scientific journals( e. g., Nature’ s Scientific Reports)
• successful initial founders’ round to be followed by private investment.
TRL 3
Multidisciplinary team
Healthy Living
Sevren is pioneering liquidcrystal – based optical neural interfaces( optrodes) that capture brain signals as light, enabling ultra-scalable, noise-immune brain-machine communication. The patented technology eliminates wiring and noise issues associated with electrodes, with a validated 232-channel optrode array prototype demonstrating superior resolution and scalability compared to conventional electrical BMIs.