Realize fears are normal.
Socializing is a perfect oppportunity for rejection, and no one wants to be rejected. If you start talking to someone, there is a chance they may find you boring. But at the same time, there will be people who think you are interesting and fun. It's okay to be nervous, but trust that the people you're meant to connect with will find you.
Start the conversation.
Chances are that other people in the room are nervous too. When you begin the conversation you take the pressure off them and end the awkard silence. It gets easier and more natural with practice. You could start with something as simple as: "Where are you from?" or "I love your jacket. Where'd you get it?"
Know what's going on.
The more you know about what's going on in the world the better your chances are of finding something to talk about. In conversation be prepared to talk about something you found interesting recently. Start with something like: "I saw the funniest thing yesterday," or "Did you see that article about...?"
Take a sincere interest in the other person.
People are most often drawn to those who make them feel comfortable and show a real, genuine interest in them. True connection requires empathy, so make sure you give as much as you take.
Learn to read body language.
Look for non-verbal cues. You don't want to be that person who traps someone in a conversation or the last one at the party who hasn't picked up on the fact that it's time to go. At the same time, you may notice that there's someone else who seems to be nervous, and you could try talking to them to ease both of your anxieties.
Take a friend.
Entering into a new social situation is always easier if you go with a friend. It helps to know someone who likes you is there with you, which might help you feel condident enough to talk to someone new.