UAB Insight Neurosciences Volume 5 - Page 2

UAB MEDICINE NEWS UAB Neurosciences Expands Faculty, Services UAB Neurosciences has expanded its faculty and services in and a neurocritical care and stroke fellowship at the at UAB funded by the National MS Society, will join Google Glass, VIPAAR Combine for Telemed Surgery Chambers, DVM, MD, coprincipal investigator of EVOLVE, the following areas: University of California, San Francisco (UCSF). Hays the faculty this summer. A graduate of the University A virtual, augmented, reality technology called VIPAAR used in (Evaluation of Outcomes for Quality of Life and Activities of has served on the faculty at Medical University of South of Mississippi School of Medicine, he completed his Carolina, where she was director of the Neurology neurology residency at UAB. He is interested in clinical conjunction with Google Glass could be an important step toward Daily Living for BKP in the treatment of VCFs), a long-term prospective observational trial at more than 20 US medical the development of useful, practical telemedicine, says UAB enhanced with the addition of faculty members John Residency and Neurocritical Care Fellowship programs. care and research related to multiple sclerosis and other neurosurgeon Barton Guthrie, MD. Guthrie developed VIPAAR centers. “Compression of the vertebra adds stress to adjacent Deveikis, MD, and Angela Hays, MD. She will direct the neurology critical care program and demyelinating disorders. (Virtual Interactive Presence in Augmented Reality) over the vertebrae and can result in new fractures with even further Agnihotri earned her MD degree from Government past decade to allow real-time, inter active video conferencing. increases in pain,” says Chambers. “Quality of life is threatened Medical College, Bhavnagar, India, and completed her In September 2013, VIPAAR and Google Glass, the wearable and increased mortality following osteoporotic fragility residency in neurology at the University of Connecticut, computer with head-mounted optical display, were used for the fractures has been reported. The consequences of inactivity • Stroke interventional and critical care resources are Deveikis, an interventional neuroradiologist, earned expand its complement of vascular neurologists. his MD degree from the University of Massachusetts Medical School, where he also completed a radiology • The UAB Epilepsy Program, one of the nation’s residency.  He also completed fellowships in largest, continues to grow with the addition of Siddharth Farmington. She finished a fellowship in advanced neuroradiology at Georgetown University Medical Kharkar, MD, to the faculty. general neurology at Massachusetts General Hospital, first time in a surgery. One surgeon performed a major procedure in this population are significant and may be irreparable.” She at UAB while another physician watched and interacted from an notes EVOLVE comes at a time when surgeons are seeking Center, Washington, DC, and at the University of Boston, and a fellowship in neurology-HIV at Beth office in Atlanta. The built-in camera transmitted the image of alternatives to current medical and surgical strategies for Western Ontario, London, Canada. He has more than 25 Kharkar, who will be the UAB Magnetoencephalography (MEG) director and has particular expertise in Israel Deaconess Medical Center, Boston. Her areas of the surgical field to Atlanta, and VIPAAR allowed the observing patients with painful vertebral fractures. Chambers and her years of neurointerventional experience, with particular evaluating patients for epilepsy surgery, earned his medi- interest are neuroinfectious disease, HIV neurology, and doctor watching on his computer monitor to introduce his colleague Patrick Pritchard, MD, have the largest cohort of expertise in diagnostic cerebral and spinal angiography, cal degree from Seth G.S. Medical College and K.E.M. neurological complications of systemic diseases such as hands into the virtual surgical field, where they were seen in the kyphoplasty patients in Alabama, and the first of a planned 50 tumor embolization, vascular malformations, and Hospital, Mumbai, India, and his MHS degree from the sarcoidosis, lupus, Sjogren’s syndrome, and vasculitis. pediatric neurointervention. He is the coauthor, along Johns Hopkins School of Public Health, Baltimore. He operating surgeon’s head-mounted display. The display is similar patients was enrolled in the trial at UAB in January. For more to how television producers can insert a virtual yellow first-down information about EVOLVE at UAB, call 205.481.7938 or with Mark Harrigan, MD, of the UAB Department of completed his neurology fellowship at Hahnemann Uni- Neurosurgery, of the Handbook of Cerebrovascular versity Hospital, Philadelphia, and a fellowship in neuro- Rhodemarie Maron, DO, UAB Neurology will open point out anatomy, provide guidance, or demonstrate the proper Disease and Neurointerventional Technique (Springer), physiology and epilepsy at UCSF. His epilepsy research a new general neurology practice at UAB Hospital- positioning of instruments. VIPAAR is now commercialized at a which is now in second edition. His primary appointment includes language lateralization, ictal EEG pattern in Highlands. Maron is a graduate of the Kansas City at UAB is in the Department of Neurosurgery. His arrival autoimmune encephalitis, and flow-controlled CSF drain- University of Medicine and Biosciences and completed technology business incubator partnered with UAB. “This system UAB Neurosurgery’s R. Shane Tubbs, PA-C, PhD, started lets an expert guide and teach new skills while enhancing patient as a surgeon assistant before becoming a neuroanatomist ensures that acute stroke care and neurointerventional age in hydrocephalous. a neurology residency at UAB and a neuro-oncology safety and outcomes,” says Guthrie. services are now available at UAB 24 hours a day, 7 days • With Agnihotri’s arrival, along with new physician line on a football field. With the technology, a remote surgeon can email mhowens@uabmc.edu. Tubbs: Surgeon Assistant and Neuroanatomist and the editor-in-chief of Clinical Anatomy. Now he is the newest editor for the 41st edition of Gray’s Anatomy and an fellowship at Duke University Medical Center, Durham, North Carolina. Maron previously practiced general and Szaflarski Named to Epilepsy Committee editor for the 5th and 6th editions of Netter’s Atlas of Human Multiple Sclerosis expands with the additions of William neuro-oncology in Tupelo, Mississippi. Her practice Neurologist Jerzy Szaflarski, MD, PhD, was recently named to Anatomy, the best-selling anatomy books in the world. Last of Medicine. She completed a neurology residency at Meador, MD, and Shruti Agnihotri, MD. Meador, who includes oncology patients who have neurologic the American Epilepsy Society-NINDS Research Benchmarks year Tubbs authored, with pediatric neurosurgeon Jerry Washington University School of Medicine, St Louis, is finishing a neuroimmunology clinical care fellowship conditions. Stewards committee. The newly established AES committee is Oakes, MD, The Chiari Malformations, and 2014 will see his charged with promoting and tracking progress in areas targeted contributions to Wiley’s unique text showcasing variations a week.  Hays is a graduate of the Tulane University School continued from cover Guthrie says the unique focus of N²QOD on effectiveness of the surgical intervention gives participants the tools to assess, on a national and • The UAB Division of Neuroimmunology and as potential epilepsy benchmarks. Szaflarski, director of the in normal human anatomy, Bergman’s Textbook of Human AANS saw fit to become the first national society to Forty-four institutions are participating in the Lumbar UAB Division of Epilepsy, will serve a 3-year term as a steward. Anatomic Variation. Tubbs earned his PA-C degree from initiate such a program. We need all practice groups Spine registry, which has more than 7000 patients, Stewards meet annually in conjunction with the annual AES UAB and was considering entering medical school when his to participate.” and 25 sites are participating in the Cervical Spine meeting as well as such activities as symposia or publications. interest in anatomy was piqued while performing cadaveric registry, which numbers more than 1000 patients. Szaflarski joined UAB in 2012. dissection that led to findings published in the Journal of He notes that the database also can provide local scale, the actual impact of the neurosurgical satisfaction of external requirements such as licensing service on patients’ lives. “In other words, N²QOD and maintenance of specialty board certifications. This is the largest spine surgery registry in existence. Neurosurgery. He subsequently completed a master’s degree EVOLVE Assesses Balloon Kyphoplasty and a doctorate, both at UAB. Since then he has taught gross investigator for the project; Mark Hadley, MD, A multicenter national trial is evaluating activity, quality anatomy to nurse anesthesia, surgical physician assistant, and data related to quality by providing risk-adjusted, and Beverly Walters, MD, are coinvestigators; and of life, and safety outcomes of minimally invasive balloon longitudinal performance measurement of patient- Guthrie is director of operations. The Vanderbilt healthcare reform may simply reward cheaper rather centered surgical outcomes. Modules for Lumbar Institute of Medicine and Public Health manages the dental, optometry, and medical students. He serves as a surgeon kyphoplasty (BKP) for vertebral compression fractures (VCFs), assistant at Children’s of Alabama, and neuroanatomy lecturer which affect one in three women and one in eight men age 50 to Neurosurgery residents. Tubbs has contributed to almost 850 than valuable care,” says Guthrie. “The N²QOD and Cervical Spine procedures were launched early collection and analysis, and the REDCap (Research and older and threaten patients’ mobility and quality of life. can provide the evidence we need to appropriately in 2012. Lumbar Deformity, Cerebrovascular, and Electronic Data Capture) platform provides define our value for patients. We are fortunate that the Tumor modules are among those in development. comprehensive data services. “Kyphosis compresses the thorax, reducing pulmonary function, the pediatric neurosurgery team includes looking for anatomical and the abdomen, which can lead to decreased appetite solutions to surgical issues and helping develop minimally enables neurosurgery to understand its patientcentered value proposition,” he says. “Without such evidence of patient-centered value, The N²QOD allows users to collect and track M. R. Chambers, DVM, MD, is UAB’s principal and bladder incontinence,” says UAB neurosurgeon M.R. 2 For Referrals: 800.822.6478 peer-reviewed articles and several seminal texts. His work with F E A T U RE D C L I N I C A L TR I A LS Creatine Safety, Tolerability, & Efficacy in Huntington’s Disease (CREST-E). The purpose of the study is to assess whether high doses of creatine can slow down the worsening of Huntington’s Disease symptoms that occur over time. Brain cell injury and death is believed to cause the symptoms of HD. A major factor in the brain cell death is thought to be a lack of normal levels of cell energy and the generation of harmful free radicals. Creatine is a dietary supplement believed to help the body produce energy. High doses of creatine may help protect brain cells in people who have HD by improving the levels of cell energy. NCT00712426. PI: Victor Sung, MD. Contact: Jenna Smith, 205.975.0338. Post-Stroke Aphasia and rTMS Treatment Study (PART). This is a study to learn how repetitive transcranial magnetic stimulation (rTMS) at different durations affects language recovery in patients with chronic aphasia after stroke. This noninvasive method to excite neurons in the brain involves weak electric currents induced in the tissue by rapidly changing magnetic fields (electromagnetic induction). This way, brain activity can be triggered or modulated without the need for surgery or external electrodes. NCT01512264. PI: Jerzy Szaflarski, MD. Contact: Amber Martin, 205.934.3866. Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR III). This 5-year, phase 3 clinical trial aims to obtain information from a population of 500 intracerebral hemorrhage (ICH) subjects with intraventricular hemorrhage (IVH) testing the benefit of clot removal for IVH. The study will compare extraventricular drainage (EVD) use plus recombinant tissue plasminogen activator (rt-PA, Cathflo Activase Genentech, Inc, San Francisco) with EVD+ placebo in the management and treatment of subjects with small ICH and large intraventricular hemorrhage (ICH <30 cc and obstruction of the 3rd or 4th ventricles by intraventricular blood clot). NCT00784134. PI: Mark Harrigan, MD. Contact: Lisa Nelson, research coordinator, 205.934.3131. invasive techniques. M o r e I nf o r ma t i o n : u a b m e d i c i n e . o r g / p h y s i c i a n 3