UAB Insight Cancer Volume 2 - Page 3

P U B L I C AT I O N S O F N OT E UAB MEDICINE NEWS NCCN Taps UAB for Affiliate Research trials, continuing medical education for nurses and oncologists, The NCCN Affiliate Research Project (ARP) has qualified its and access to the latest education about advancements in the first seven sites, naming community-based affiliates from the treatment and detection of cancer. UAB Cancer Care Network, Fox Chase Cancer Center, and Seattle Cancer Care Alliance. The qualified UAB Cancer Care Network member is Medical Center of Central Georgia, in Macon. ARP was developed by the NCCN Oncology Research Program, which has received more than $36 million in research grants from pharmaceutical and biotech companies to support investigator-initiated trials. Affiliate sites will have access to new and innovative cancer drugs for their patients in collaboration with NCCN member institutions, and principal investigators of NCCN-funded studies will have access to these community sites. Huh Receives Cancer Society QOL Award Gynecologic oncologist Warner Huh, MD, was awarded the American Cancer Society’s 2012 Lane W. Adams Quality of Life Award at its annual board meeting in May. The award recognizes those whose innovation, leadership, and consistent excellence provide compassionate, skilled care and counsel to cancer patients and their families. Huh, chair of the robotic surgery program at UAB, has played a major role in the development of the first proven cervical cancer vaccine. He is on the steering committee of the Johns Hopkins/UAB/University of Colorado SPORE in Cervical Cancer. Cancer Care: Looking at Cost With a $15 million Health Care Innovation Challenge Grant from CMS, UAB’s Comprehensive Cancer Center (CCC) will deploy its Deep South Cancer Navigation Network in a program to find upwards of $50 million in cancer care costs savings over 3 years. The initiative will help cancer patients facing advanced stages of disease and their physicians make the most appropriate choices for treatment, reduce the use of ineffective therapies, and maximize the appropriate use of health care resources. UAB Awarded $19 Million Disparities Grant A 5-year, $19-million NIH award has renewed the partnership of UAB’s Comprehensive Cancer Center, Morehouse School of Medicine (MSM) in Atlanta, and Tuskegee University (TU) in Alabama. It seeks to understand cancer disparities and determine methods to solve them. UAB pathologist Upender Manne, PhD, is lead principal investigator. The initial grant trained 81 scholars to increase the number of minorities engaged in cancerrelated research. The schools all saw substantial increases in cancer research funding, MSM established a 30-member cancer research program, and TU increased its cancer research capacity with new trainees and cancer-related courses. The National UAB Cancer Care Network Expands Further Center for Bioethics in Research and Health Care at TU was UAB’s Cancer Care Network, established in June 2011 to established as a national resource. In addition, UAB recruited 6 enhance oncology services in the region by joining forces faculty engaged in cancer-health disparities. with community cancer centers, has added 2 more centers and now serves 8 communities in 3 states. The affiliation program added Marshall Medical Centers in Guntersville and Boaz, Alabama, and Fort Walton Beach Medical Center in Florida. “With these affiliations, our 350 linicians, cancer scientists, clinicians, f and a large array of services are linked to n local oncologists in nd communities around the South, so patients can receive benefit of the he UAB Comprehensive Cancer ive Center’s expertise without leaving their hometown area,” says Edward Partridge, MD, director of the UAB d Comprehensive Cancer Center. The affiliations provide access ancer to UAB’s best practices in cancer care, broader access to clinical ctices Cardan Wins Award From American Association of Physicists in Medicine Beriwal S, Demanes DJ, Erickson B, Jones E, De Los Santos JF, Cormack RA, Yashar C, Rownd JJ, Viswanathan AN. “American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer.” Brachytherapy. 2012 Jan;11(1):68-75. Heath CH, Sorace AG, Knowles JA, Rosenthal E, Hoyt K. “Microbubble therapy enhances anti-tumor properties of cisplatin and cetuximab in vitro and in vivo.” Otolaryngol Head Neck Surg. 2012 Jun;146:938-945. Kim KH, Dmitriev I, O’Malley JP, Wang M, Saddekni S, You Z, Preuss MA, Harris RD, Aurigemma R, Siegal GP, Zinn KR, Curiel DT, Alvarez RD. “A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer.” Clin Cancer Res. 2012 Apr 17. [Epub ahead of print]. Hung J, Shen S, De Los Santos JF, Kim RY. “Image-Based 3D Treatment Planning for Vaginal Cylinder Brachytherapy: Dosimetric Effects of Bladder Filling on Organs at Risk.” Int J Radiat Oncol Biol Phys. 2012 Jul 1;83(3):980-5. Warram JM, Sorace AG, Saini R, Borovjagin AV, Hoyt K, Zinn KR. “Systemic delivery of a breast cancer-detecting adenovirus using targeted microbubbles.” Cancer Gene Ther. 2012 Aug;19(8):545-52. Rex Cardan, PhD, assistant professor in the Department of Radiation Oncology, won the Young Investigator Award for work presented at the 2012 annual meeting of the th F E AT U R E D CLINICAL TRIAL A American Associatio of Physicists in Medicine, July American Association 2012, in Charlotte, Nort Carolina. The work was “Fast No North and Accurate Patien Specific Collision Detection Accurate Patient u for Radiation Th R Radiation Therapy.” He and his team created a fast system that makes radiation therapy th treatments safe by detecting and avoiding safer potential collisio that can occur between the collisions patient and the accelerator. Study of Whole-Brain Radiotherapy in Combination with Concurrent Lapatinib in Patients with Brain Metastasis From HER2Positive Breast Cancer – A Collaborative Study of RTOG and KROG. RTOG 1119. This randomized phase 2 trial in patients with HER2+ stage IV breast cancer and MRI evidence of brain metastasis will evaluate randomized patients receiving whole-brain radiation alone versus patients receiving whole-brain radiation therapy plus a concurrent dosage of lapatinib. NCT01622868. PI: Jennifer De Los Santos, MD. Contact: Anna Messer, research coordinator, 205.975.2880. MOR E INF OR M AT ION: /physician 3