TTO_Grant Catalogue Grant Catalogue | Page 78

Neurophysiology and Computational Modeling of ActionObservation ABSTRACT 2014 Grants Economics and Administrative Sciences In this project we aim to challenge the current mirror neuron -MN- theory and to reach a better explanation of the MN phenomenon. For this we will take advantage of computational modeling and single cell recording method that provides information of high temporal resolution about the signals carried by neurons and is the most suitable technique to yield information about the high level functions of the primate brain, as well as providing the most precise data for computational modelling. This information will beinterpreted with a computational modelling perspective to reveal causally complete description of the brain mechanisms responsible for action understanding. The activity of single neurons will be recorded from the premotor areas F5 and F2, as well as from the primary motor cortex (MI) of trained macaque monkeys that will either perform themselves or obeserve the experimenter executing reaching-to-grasp movements in order to: (i) both characterize the observation elicited response of F5 neurons by assessing the response triggering features of the observed movement as well as the timing relationship between the response and the movement, and to provide precise data for computational modelling (ii) explore whether F2 and MI contain neurons responding to observation, characterize their observation elicited responses and compare them with those of area F5. The data obtained from the experiments will be used to construct a computational model of the action understanding process. The model will address cortical dynamics at diverse levels (i.e. neural, regional or network scale) and will comply with the empirical data (high temporal resolution signals obtained in the present study and available in the literature). Doç. Dr. Erhan Öztop DEPARTMENT Computer Science CONTACT [email protected] FUNDING SCHEME TÜBİTAK 2520 -GSRT START DATE 01.10.2013 DURATION 24 months OZU BUDGET 54.268.00 TL 78