The Trees Inside Our Brain | Page 6

What causes autism? The current scientific consensus is that autism is caused by both genetic mutations and some environmental factors. Genetics likely play the main role in causing autism. Many different genes have been identified as being associated with symptoms of autism, but researchers still cannot zero in on one causal gene. In light of recent autism research, many researchers who study autism now speculate that autism is the product of mutations in many different genes that work together. Since there are many types of autism (it’s a spectrum disorder), it seems plausible that there are mutations in different genes that are responsible for each type of autism. When these genes are identified as mutated in autistic patients, researchers often create mice that have the same mutation in order to study the gene. Some genes scientists are currently studying for their association with autism include: JAKMIP, Nlgn3, Fmr1, 15q11-13, CYFIP1, Shank3, Tsc1, 16q2.2, and more. In addition to genetics, some researchers believe autism can be caused by certain environmental factors. Environmental factors that researchers are investigating in connection to autism are based on the health of the mother. Infection, valproic acid (found in some medicines), and stress level of the mother during pregnancy may have an effect on whether or not the child will have autism. Numerous studies have concluded that environmental factors such as pesticides, GMOs, and vaccines do not cause autism.