THE REALITIES ABOUT POULTRY The Modern Farm - The Realities About Poultry_Seco | Page 120

anpolymyxinantibiotic with bactericidal activity against organisms susceptible to amoxicillin and colistin in
Gram-negative bacteria such as Salmonella and E. coli. calves, goats, poultry, sheep and swine. These
After
oral
administration, micro-organisms
amoxicillin is well absorbed and widely distributed in the Clostridium,
include
Campylobacter,
Corynebacterium,
body. Amoxicillin acts by inhibiting bacterial cell Erysipelothrix,
Haemophilus,
E.
coli,
Pasteurella,
membrane synthesis. Colistinsulphate binds to the cell Salmonella, penicillinase-negative Staphylococcus
membrane of Gram-negative bacteria and compromises and Streptococcus spp.
the membrane integrity. The cell membrane disrupting
activities of colistin and amoxicillin work synergistically Side effects:
to disrupt the cell structure of pathogens, giving excellent Animals can experience hypersensitivity reactions,
bactericidal properties.
renal
dysfunction,
neurotoxicity
and
neuromuscular blockade.
Composition per gram powder:
Amoxyicillintrihydrate 200 mg. Dosage:
Colistinsulphate 1 200 000 IU. For oral administration.
Excipients ad 1 g. Calves, goats and sheep:
Twice daily 5 gram per 100 kg body weight for 3 –
Withdrawal times:
5 days.
For meat: 8 days
Poultry and swine:
Packaging:
1 kg per 1000 – 2000 liters of drinking water for 3
Dimoxan WS is available in sachets of 100 gram and jars – 5 days.
Note: Before adding to the drinking water make a
of 1000 gram.
pre-solution of 1 kg Dimoxan WS per 20 liters of
water with a temperature of 40 °C
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