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2.6 Ignoring time in processes Specific claim Since we cannot calculate mortality and morbidity for lack of reliable data, let’s put the dubious ratios aside and use only the most accurate reports we have - the Diamond Princess numbers. Coronavirus caused an unusual number of deaths, seven on a single ship. It cannot be compared to the flu. Diamond Princess quarantine wasn’t an instantaneous event. It was a process that took about four weeks. It’s a relatively short time, so it might seem that adjustments for baseline mortality are negligible. It turns out otherwise. Let’s examine the numbers. From February 2nd 2020 to March 1st 2020, 7 people died on Diamond Princess. How many people would have died in normal circumstances (in the absence of coronavirus)? Since the majority of the passengers were Japanese, for best approximation we use data from the mortality database from the Japan National Institute of Population and Social Security Research. [22, 23] In Table 2 we use the crude mortality rate per age group to estimate the expected number of deaths per year that would happen on Diamond Princess in the absence of special conditions. Age group 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80-89 90-99 Crude mortality rate (actual data for Japan from 2016 that serves as an estimate for 2020) 0.002260 0.000276 0.000756 0.001122 0.002524 0.006265 0.015194 0.038053 0.124751 0.390717 Total: Persons aboard Expected deaths per year 16 23 347 428 334 398 923 1015 216 11 3711 0.04 0.01 0.26 0.48 0.84 2.49 14.02 38.62 26.95 4.30 88.01 Table 2: Expected deaths per year for the Diamond Princess population We limit our analysis to the quarantine period from February 2nd to March 1st which is 29 days. Assuming a uniform distribution we expect 7 (29/365*88) deaths during this period. If we redo the calculations with the updated data on the resolved cases on March 28th, we get 12 actual deaths on Diamond Princess and 13 expected deaths in the period from February 2nd to March 28th 2020 We need to remember that this number is encumbered by selection bias. We are applying crude mortality rates of population of Japan to the subpopulation that is not matching in terms of ethnicity and social status. In particular the cruise ship population is likely characterized by: • higher than average socioeconomic status • better access to health care • healthy enough to be able to travel Time cannot be ignored. We should consider the expected number of deaths in the same period in normal (infection-free) circumstances. Although there is an unknown margin of error related to selection bias, knowing that with the number of actual deaths on Diamond Princess we didn’t 8