The META Scholar Volume 1 | Page 22

Med Equipment & Diagnosis Page 22 TMS Pericarditis Cont. the impact a slight deviation in an un-calibrated ECG device can cause to a patient. Let’s look even further into the cell membrane to determine what causes the resting cell membrane potential that the isoelectric point is referenced. Bioelectricity: A potential exist due to differences in ion potentials across a cell’s semi permeable membrane. Many ions exist inside and outside the cell. However, certain ions exist in higher concentrations at resting states; potassium, K+,exist inside the cell in higher concentrations while, sodium, Na+,exist outside the cell in higher concentrations. (fig. 4) The concentrations of these ions at resting state produce what’s called the resting membrane potential. The ECG does not measure this resting membrane potential rather measures the vector, amplitude and direction of the signal as it changes. Looking at the diagram of the cell below, at resting potential Na+ is found outside the cell and K+ is found inside the cell. Voltage gated channels found within the cell membrane initiates an influx of sodium into the cell, which is depolarization, while potassium exits. As the ions return back to normal, the cell is said to be repolarized. This concentration in ions travels down the cell, so does the membrane potential. This is how the membrane produces the resting potential and how that potential travels down the cell. There are many more biochemical reactions that occur, but for the sake of this article, we will save that for another edition. These electrical properties are what result in the isoelectric line in the ECG waveform. A patient with a disease resulting in pericarditis, the inflammation in the pericardium will cause changes in these electrical properties. (fig. 5) A Biomed should not only know what they are doing but look into why they are doing it. This is when you can become more effective to the healthcare team. Knowing what happens from the physiology, the biophysics, to the medical device, and how any pathology can change the normal physiology to include the biophysics, causes distinct changes of the indicators in the device display. BMETs and Clinical Engineers often speak of becoming more involved in the clinical aspect of the job. While there are no clinical duties involved with learning about medical devices and medical diagnosis, as of yet, we should strive to explore new and old areas to ensure we are providing everything we can. …(Continued on next page) Fig 4. Resting Potential heart cell: Negative ions (K-) that are INSIDE the cell. Positive ions (Na ) are OUTSIDE the cell. Photo by BMETWiki University. Fig 5. Movement of cells between depolarization and repolarization cycles.