The pain associated with this condition is a
serious complication.
Highly flexible fingers and toes
Loose, unstable joints that are prone to:
sprain, dislocation, subluxation
(partial dislocation) and hyperextension
(double jointedness)
Flat feet
Joint pain without inflammation
Fatigue, which can be debilitating
High and narrow palate,
resulting in dental crowding
Vulnerability to chest and sinus infections
Easy bruising
Fragile blood vessels resulting from
cystic medial necrosis with tendency
towards aneurysm
(even abdominal aortic aneurysm)
Velvety-smooth skin which may be
stretchy and is often translucent, with
blue veins clearly visible on limbs and
particularly in the hands
Abnormal wound healing and scar
formation
(scars may appear like cigarette burns)
Low muscle tone and muscle weakness
Early onset of osteoarthritis
Cardiac effects: Dysautonomia typically
accompanied by Valvular heart disease
(such as mitral valve prolapses, which
creates an increased risk for infective
endocarditis during surgery, as well as
possibly progressing to a life-threatening
degree of severity of the prognosis of mitral
valve prolapse)
Difficulty regulating own body
temperature
Insensitivity to local anaesthetics.
Migraines and headaches, including
postural headaches from spontaneous
intracranial hypotension.
Fibromyalgia symptoms:
Myalgia and arthralgia
Other, less common signs and complications
may include:
Osteopenia (low bone density)
Talipes equinovarus (club foot),
especially in the Vascular type
Deformities of the spine, such as:
Scoliosis (curvature of the spine),
Kyphosis (a thoracic hump),
Tethered spinal cord syndrome,
Occipitoatlantoaxial hypermobility,
Arnold-Chiari malformation (brain
disorder).
Functional bowel disorders (functional
gastritis, irritable bowel syndrome)
Gastroparesis
Nerve compression disorders (carpal
tunnel syndrome, acroparesthesia,
neuropathy)
Vascular skin conditions: Raynaud's
phenomenon, Livedo reticularis
Blue sclera
Arachnodactyly
Otosclerosis (hearing loss)
Premature rupture of membranes during
pregnancy
Platelet aggregation failure
(platelets do not clump together properly)
Infants with hypermobile joints often
appear to have weak muscle tone
(hypotonia), which can delay the
development of motor skills such as
sitting, standing, and walking
Arterial/intestinal/uterine fragility or
rupture
Swan neck deformity of the fingers