The Leaf THE LEAF November-December 2019 | Page 16

We demonstrate here that both HU210 and the endocannabinoid AEA promote proliferation of embryonic hippocampal NS/PCs without significant effects on their differentiation, resulting in more newborn neurons. The effects of HU210 on adult hippocampal neurogenesis were quantified in freely moving rats and were correlated with behavioural testing. We show that 1 month after chronic HU210 treatment, rats display increased newborn neurons in the hippocampal dentate gyrus and significantly reduced measures of anxiety- and depression-like behaviour. Thus, cannabinoids appear to be the only illicit drug whose capacity to produce increased hippocampal newborn neurons is positively correlated with its anxiolytic- and antidepressant-like effects. https://realfarmacy.com/3-studies-that-show- cannabis-grows-brain- cells/?fbclid=IwAR127eLwA3TzfCMxJjyKpr- _8fB7eyHi7-_-wqrrscAQ3EhWSOdi-l5YCd4