When cannabinoid receptors are stimulated, a
variety of physiologic processes begin.
Researchers have identified two cannabinoid
receptors: CB1, predominantly present in the
nervous system, connective tissues, glands,
and organs, and CB2, predominantly found in
the immune system.
Many tissues contain both CB1 and CB2
receptors, each linked to a different action.
Endocannabinoids are substances our bodies
naturally make to stimulate CB1 and CB2
receptors.
The two most well understood of these
molecules
areanandamide
and
2-
arachidonoylglycerol (2-AG), they are
synthesized on-demand from cell membrane
arachidonic acid derivatives, have a local
effect and short half-life before being
degraded by the enzymes fatty acid amide
hydrolase (FAAH) and monoacylglycerol
lipase (MAGL).
What are Cannabinoids
Cannabinoids are naturally occurring
compounds found in the cannabis sativa plant,
active chemicals in cannabis that cause drug-
like effects throughout the body, including the
central nervous system and the immune
system.
They are also known as Phytocannabinoids.
The main active cannabinoid in cannabis is
delta-9-THC.
Another active cannabinoid is cannabidiol
(CBD), which may relieve pain and lower
inflammation without causing the "high" of
delta-9-THC.
Cannabinoids may be useful in treating the
side effects of cancer and cancer treatment.
Other possible effects of cannabinoids may
include:
• Anti-inflammatory activity
• Blocking cell growth
• Preventing the growth of blood vessels
that supply tumours
• Antiviral activity
• Relieving muscle spasms caused by
multiple sclerosis
What is CBD?
CBD is short for cannabidiol- is one of at least
113 active cannabinoids identified in
cannabis. It is a major Phytocannabinoid
accounting for up to 40% of the plant's
extract.
CBD is considered to have a wide scope of
potential medical applications - due to clinical
reports showing the lack of side effects,
particularly a lack of psychoactivity (as is
typically associated with ∆9-THC), and non-
interference with several psychomotor
learning and psychological functions.
CBD produces some of the same (well
researched) medical benefits of THC
(tetrahydrocannabinol) without the high.
Terpenes
Terpenes are a large and diverse class of
organic compounds, produced by a variety of
plants that are the major components of resin
offering their lush aroma.
In 3 seconds, the body responds to the aroma
of an oil.
It profoundly impacts the nerves, cells, and
mood via the limbic system of the brain.
Terpenes and terpenoids are the primary
constituents of the essential oils of many types
of plants and flowers and are derived
biosynthetically from units of isoprene, the
isoprene units linked together and form linear
chains, as chains of isoprene units are built up,
the resulting terpenes are classified
sequentially by size as hemiterpenes,
monoterpenes, sesquiterpenes, diterpenes,
sesterterpenes, triterpenes, and tetraterpenes.