The Leaf THE LEAF May-June 2018 | Page 19

As mentioned before, there are about 120 terpenes found in cannabis. They coexist in the herb with cannabinoids like THC and CBD (sometimes even working with them for our better experience), but they are not psychoactive like THC. Some of those terpenes can be found in other plants, while others are exclusive to cannabis. But, It’s not all about the smell, though. Terpenes also have therapeutic properties and can aid in plant’s medical effects: Research on medical properties of terpenes in cannabis Some terpenes are very effective in relieving stress, others are great when you need to relax, while there are some that boost focus. There are many options here, as you’ll have a chance to see. For example, myrcene induces sleep, while limonene uplifts our mood. They interact with our endocannabinoid system and assist cannabinoids in entering the bloodstream, in a process called the entourage effect. In recent years, terpenes found in cannabis became an important subject of scientific research. It was Jürg Gertsch who first noticed the ability of beta-caryophyllene to bind to the CB2 receptors, calling it “a dietary cannabinoid”. Myrcene, for instance, increases cell permeability and allows cannabinoids to be absorbed faster than they would on their own. He also concluded that all green vegetables that contain this terpene are extremely beneficial for human use. Limonene is responsible for increasing serotonin levels which influences how weed affects our mood. That means these terpenes can influence neurotransmitters in our brain which entails that different strains may have different effects on our mood. Shortly after that, Dr. Ethan Russo published an article in 2011 in British Journal of Pharmacology, which pointed to all the therapeutic properties of terpenes in marijuana, especially those missing in cannabis products that only contain CBD. Terpenes and the “Entourage Effect” explained… The “Entourage Effect” is a term coined by S. Ben-Shabat and Raphael Mechoulam back in 1998 to represent the biological synergy of cannabinoids and other compounds like flavonoids and, of course, terpenes. According to Chris Emerson, these compounds work together to make “the sum of all the parts that leads to the magic or power of cannabis”. When terpenes work with cannabinoids like CBD and THC, they form a synergy that creates stronger and better effects than both would achieve on their own. This symbiosis between cannabinoids and terpenes is what gives cannabis its special powers, as it improves the absorption of cannabinoids, overcomes bacterial defence mechanisms and minimises any side effects. He discussed the cannabinoid-terpene interaction as a “synergy with respect to treatment of pain, inflammation, depression, anxiety, addiction, epilepsy, cancer, fungal and bacterial infections”. Further research discovered that terpenes, terpenoids, and cannabinoids have the potential to kill respiratory pathogens, for instance, the MRSA virus. However, that’s not even half of the story. Terpenes have a lot more health effects which we’ll discuss next.