The Journal of the Arkansas Medical Society Med Journal Jan 2019 Final 2 | Page 15
Table 1. DSM-5 Criteria for Substance Use Disorder
A problematic pattern of substance use leading to clinically significant impairment or
distress, as manifested by at least two of the following:
Substance is often taken in larger amounts or over a longer period than was intended.
There is a persistent desire or unsuccessful efforts to cut down or control substance
use.
A great deal of time is spent in activities necessary to obtain substance, use substance,
or recover from its effects.
Craving, or a strong desire or urge to use substance.
Recurrent substance use resulting in a failure to fulfill major role obligations at work,
school, or home.
Continued substance use despite having persistent or recurrent social or interpersonal
problems caused or exacerbated by the effects of substance.
Important social, occupational, or recreational activities are given up or reduced.
Recurrent substance use in situations in which it is physically hazardous.
Substance use is continued despite knowledge of its having caused or exacerbated
persistent or recurrent physical or psychological problems.
Tolerance
Withdrawal
epines and sedative hypnotics) and those who
have had prior alcohol withdrawal experiences.
Less than 10% of individuals in alcohol with-
drawal ever demonstrate withdrawal delirium or
withdrawal seizures. Moreover, confusion and
changes in consciousness are not core criteria
for alcohol withdrawal, though alcohol withdrawal
delirium may occur. Older adults are likely more
vulnerable to withdrawal delirium, which typically
presents in the context of other clinically relevant
medical conditions.
A particular vulnerability of older adults is
that unintended alcohol withdrawal in hospitalized
patients for whom a diagnosis of AUD has been
overlooked can add to the risks and costs of hos-
pitalization.
General risks of alcohol use in later life include
the following: (1) increased brain susceptibility to
the depressant effects of alcohol, (2) decreased
rates of liver metabolism of alcohol and other sub-
stances, (3) decreased percentages of body water
and lean body mass, and (4) diminished aware-
ness. 1 All of these factors may result in more severe
intoxication and subsequent problems at lower lev-
els of consumption – especially when associated
with other medical complications.
It should be noted that while most drinkers
sometimes consume enough alcohol to feel intoxi-
cated, only a minority (less than 20%) ever develop
AUD. 3 Therefore, drinking, even daily, in low doses
and occasional intoxication do not, by themselves,
warrant a clinical diagnosis. However, it is also
true that many alcohol users who do not meet
diagnostic criteria for AUD unwittingly drink more
than is recommended by the CDC to minimize
health risks. CDC defines excessive drinking as
“heavy drinking and binge drinking.”
Table 2 outlines the CDC’s definitions of
light, moderate, and heavy drinking, as well as
what constitutes a drink.
Table 2. CDC’s Definitions for Alcohol Use 4
Light Drinking
For the majority of diseases linked to alcohol,
the risks increase with increasing consumption
– without a threshold under which there is no in-
creased risk. Table 3 identifies a broad variety of
health risks associated with excessive alcohol use.
A variety of cancers are associated with ex-
cessive alcohol use. These include: liver, mouth,
throat, larynx, esophagus, breast, and colon. The
risk varies by type of cancer, and the greatest risks
are associated with moderate to heavy use. Some
risk persists at even low levels of use. 6
Safety risks associated with excessive alco-
hol use include: MVAs, falls, drowning, burns, fire-
arm injuries, unsafe sex, domestic violence, homi-
cide, and suicide. Additional health risks include:
(1) poor nutrition and associated vitamin deficien-
cies, (2) poor medication adherence resulting in
difficult management of all medical conditions,
and (3) diminished healthcare utilization. 3
In the recent past there has been a body of
research interpreted to suggest that a number of
positive health outcomes are associated with low-
volume alcohol use, e.g. diminished mortality due
to heart disease. However, a recent systematic
> Continued on page 160.
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< 1 drink per day for women
< 2 drinks per day for men
Moderate Drinking:
1 drink per day for women
2 drinks per day for men
Heavy Drinking:
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8 or more drinks per week for women
Empathy
15 or more drinks per week for men
Compassion
What is a Drink?
12 oz of beer
5 oz of wine
1.5 oz of 80 proof (40% alcohol) liquor
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