The Journal of the Arkansas Medical Society Med Journal Feb 2019 Final 2 | Page 11
common and noticed during childhood, our case is interesting in having
none, with only two similiar cases reported previously. 3
Treatment is directed based on the severity of the disease. Patients
with mild disease are treated with iron supplementation and blood trans-
fusion. The mammalian target of rapamycin (mTOR) has been reported
as a possible pathogenic mechanism, with potential use of sirolimus as
a treatment modality. 4 If symptoms are recurrent and severe, endoscopic
hemostasis could be attempted based on the site of the lesion with a com-
Though skin lesions are common and noticed during
childhood, our case is interesting in having none,
with only two similiar cases reported previously. 3
bination of sclerotherapy, band ligation, argon plasma coagulation, or laser
application. 5 Surgical resection is reserved for refractory bleeding or for
complications such as intussusception, intestinal torsion, and obstruction.
References
1. Fishman SJ, et al. Blue rubber bleb nevus syndrome: surgical eradication of
gastrointestinal bleeding. - PubMed - NCBI. 2017.
2. Jin XL, et al. Blue rubber bleb nevus syndrome: a case report and literature
review. - PubMed - NCBI. 2017.
3. Selinger AG, Abdelhai A, Jamie W, Stephen. Blue rubber bleb nevus syn-
drome: a rare presentation of late-onset anemia and lower gastrointestinal
bleeding without cutaneous manifestations. 2016.
4. Yuksekkaya H, et al. Blue rubber bleb nevus syndrome: successful treat-
ment with sirolimus. - PubMed - NCBI. 2017.
5. Wu C, et al. Endoscopic management of blue rubber bleb nevus syndrome
in the colon with hemostatic clamp and snare. - PubMed - NCBI. 2017.
Note: For a copy of the video, please email: [email protected]
Figure 4.
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