The Journal of the Arkansas Medical Society Issue 6 Volume 115 | Page 11
Special Section: Short Dermatological Cases
Derm Dilemma:
Keratoacanthoma
Hunter Cochran 1 ; Kevin St. Clair, MD
Candidate UAMS, class 2020
1
A
60-year-old white male presents complaining of a rapidly enlarging,
painless, centrally-umbilicated, papulonodule located on the dorsal hand. The nodule
was noted initially about five weeks ago. The patient admits he attempted to drain the
lesion at home unsuccessfully. Subsequent appropriate step(s) in the evaluation or management
of this patient should include:
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A. Destruction by cryotherapy
Empathy
B. Reassurance and observation
C. Shave biopsy
Compassion
D. Warm compresses and one-week course of oral cephalexin
E. Intralesional injection of triamcinolone acetonide
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Answer: C.
The clinical features of an erythematous, exophytic papulonodule with a central keratin-filled
crater located in a sun-exposed area coupled with relatively rapid growth suggest that this lesion
most likely represents a keratoacanthoma (KA). Most authorities consider KA a low-grade variant
of squamous cell carcinoma (SCC), although untreated KA may resolve spontaneously within a few
months. Ethical and medicolegal considerations preclude observation of suspected KA, as aggressive
and potentially metastatic SCC may present in a similar fashion.
Following definitive diagnosis via skin biopsy, the most commonly employed treatment modalities
are excision or destruction by curettage and electrodessication.
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NUMBER 6
DECEMBER 2018 • 131