The Journal of mHealth Vol 2 Issue 4 (August) - Page 16

Industry News Human Organs-on-Chips Wins Design of the Year 2015 even more to translate the Organs-onChips technology into a commerciallyavailable system that can be used to design better and safer products for humans, as well as creating a new era of applications in the personalised health space.” The Organs-on-Chips technology is based on pioneering work conducted by Donald Ingber, M.D., Ph.D. and his team at the Wyss Institute for Biologically Inspired Engineering at Harvard University. Recognised for its potential to reduce animal testing, revolutionise the development of new drugs, and open a new era of personalised health Emulate’s Human Organs-on-Chips has been named the overall winner of the ‘Design of the Year’ award by London’s Design Museum. Organs-on-Chips emulates human biology to understand how diseases, medicines, chemicals, and foods affect human health. The technology involves placing living human cells in micro-engineered environments to create a microchip embedded with hollow microfluidic tubes each lined with human cells, through which air, nutrients, blood and infectioncausing bacteria can be pumped. The chips are manufactured in a similar way to microprocessors, only instead of moving electrons through silicon, these chips push minute quantities of chemicals past cells from lungs, intestines, livers, kidneys and hearts. The microfluidic networks let the chips mimic the structure and function of complete organs, making them an excellent testbed for pharmaceuticals. The complete integrated system provides a window into the inner-workings of the human body, enabling the prediction of human response with greater precision and detail than today’s cell culture 14 August 2015 or animal-based testing. “This winning design is a great example of how design is a collaborative practice embracing expertise and know how across disciplines. Its selection as Design of the Year 2015 also signifies a desire to recognise and award design that can significantly impact society now and in the future,” said Gemma Curtin, who is the Designs of the Year 2015 exhibition curator. “This is the epitome of design innovation – elegantly beautiful form, arresting concept and pioneering application” The award is selected by design experts, practitioners, curators and academics from around the world, who were united in their responsibility to select a winner that emphasises design’s impact on our lives now and in the future, solving diverse problems with innovation and intelligence. “We are deeply honoured that our Organs-on-Chips have been awarded Design of the Year, and we are passionately following our mission to apply our new living products for a range of applications to improve human health,” said Geraldine A. Hamilton, Ph.D., President and Chief Scientific Officer of Emulate. “This prestigious recognition inspires us Each Organ-on-Chip can contain tens of thousands of cells in tiny, hollow channels and is approximately the size of a USB memory stick. The Organson-Chips are designed to recreate human biology, emulating dynamics of organs at the cellular level with unprecedented precision, reproducibility and control. Emulate’s team has designed a range of Organs-on-Chips, including the lung, gut, kidney, skin, eye, and blood-brainbarrier, which can be linked together into a ‘Human-On-Chips’ system. The products are now being used commercially to improve innovation, design and safety for industrial applications in the areas of pharmaceuticals, personalised medicine, agriculture, cosmetics and chemicalbased consumer products. This year is the first time the prestigious Design of the Year award has been presented to a product from the field of medicine, and there was strong competition from various industries, including Google’s self-driving car and several other notable designs. Human Organson-Chips received their nomination from Paola Antonelli, the Museum of Modern Art’s Senior Curator of Architecture & Design and Director of R&D. “This is the epitome of design innovation – elegantly beautiful form, arresting concept and pioneering application,” said Antonelli. Organs-on-Chips are featur VBBF