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Cite this article as: Martinez MJ, Berra I, Cornelis J, Costilla J, Zamora F & Garcia Delucis P. Use of plasmapheresis during cardiopulmonary bypass in a pediatric heart transplant of a patient with Failing Fontan Physiology: first case in Argentina. J Extra Corpor Technol 2026, 58, 79--84. https:// doi. org / 10.1051 / ject / 2025053.