The Journal of ExtraCorporeal Technology No 58-1 | Seite 67

M. Raguindin et al.: J Extra Corpor Technol 2026, 58, 57--64 61
Table 5. ECMO characteristics.
Pre-Group( N = 38)
Post-Group( N = 35)
P-Value
Type, n(%)
< 0.001
VA
36( 94.7 %)
19( 54.3 %)
VV
2( 5.3 %)
16( 45.7 %)
Cannulation site, n(%)
0.005
Central
17( 44.7 %)
3( 8.6 %)
Peripheral
21( 55.3 %)
32( 91.4 %)
Days on ECMO, median( IQR)
6.9( 3.1--10.7)
7.1( 0--17)
0.163
Indication, n(%)
N / A
Respiratory illness
5( 13.2 %)
15( 42.9 %)
COVID-19
0( 0.0 %)
9( 25.7 %)
Cardiogenic shock
11( 28.9 %)
3( 8.6 %)
Intra-procedural or intra-operative MCS
10( 26.3 %)
8( 22.9 %)
Cardiac arrest
7( 18.4 %)
4( 11.4 %)
Procedural or operative cardiac arrest
5( 13.2 %)
5( 14.3 %)
Renal failure on ECMO, n(%)
19( 54.3 %)
26( 74.3 %)
0.033
VA: Veno-arterial; VV: Veno-venous.
Table 6. Results.
Pre-Group( N = 38)
Post-Group( N = 35)
Post-Group excluding COVID-19 patients( N = 26)
P-Value
Time to two consecutive aPTTs within therapeutic
8.9( 2.0--15.8)
14.2( 4.3--24.1)
N / A
0.517
range for the initial goal range, hours, median( IQR)
N / A
8.6( 3.2--14.1)
0.615
Percent aPTTs out of range after 2 consecutive aPTTs
N / A
14.3( 3.35--25.3)
9.1( 0--20.1)
N / A
within documented therapeutic aPTT goal, median( IQR)
Percent supratherapeutic aPTT values, median( IQR)
N / A
4.7( 0--14.6)
N / A
N / A
Percent subtherapeutic aPTT values, median( IQR)
N / A
8.3( 0--19.4)
N / A
N / A
Number of bivalirudin aPTT goal adjustments, median( IQR)
N / A
1( 0--2)
N / A
N / A
Renal Failure, median( IQR)
2( 0--3)
Without renal failure, median( IQR)
1( 0--6)
Table 7. Adverse events.
Pre-Group( N = 38)
Post-Group( N = 35)
P-Value
Hgb Drop 3 g / dL, n(%)
9( 23.7 %)
4( 11.4 %)
0.172
Major Bleed, n(%)
N / A
11( 31.4 %)
N / A
Hgb Drop 2 g / dL
11( 31.4 %)
Transfusion of at least 10 mL / kg of PRBCs in 24 h
5( 14.3 %)
Type of Major Bleed, n(%)
N / A
N / A
Retroperitoneal
4( 36.4 %)
Pulmonary
1( 9.1 %)
CNS
0
Requires Surgical Intervention
2( 18.2 %)
Other
4( 36.4 %)
Systemic VTE, n(%)
3( 7.9 %)
2( 5.7 %)
0.763
DVT
1
1
PE
0
0
CNS
1
0
Intracardiac
1
1
Circuit thrombosis, n(%)
34( 89.5 %)
24( 68.6 %)
0.027
Oxygenator
34
23
Hemofilter
0
0
AV Bridges / Cannulas
0
1
Hgb: Hemoglobin; PRBCs: Packed red blood cells; CNS: Central nervous system; DVT: Deep vein thrombosis; PE: Pulmonary embolism; AV: Arterio-venous.