The Journal of ExtraCorporeal Technology No 57-3 | Page 48

158 T. Takeichi et al.: J Extra Corpor Technol 2025, 57, 153--159
and microcirculatory perfusion. The right mABP, which reached a nadir of 29 mmHg, also improved gradually until 42 mmHg. While studies have shown no significant differences in mABP between PF and NPF, indexed systemic vascular resistance( SVRi) during aortic cross-clamping was significantly lower with PF [ 14--18, 25 ].
Finally, the pulsatile method for upper body malperfusion remains a concern in its usefulness because NIRO improved, but it does not confirm improving true lumen blood flow by using echo. Therefore, this method is unprecedented, and it is uncertain whether similar results can be achieved. Also, this technique may not work in all instances, this case report is meanttoremindotherstokeepinmindthatPFisanoption we possess as a potential solution in malperfusion cases.
Funding The authors received no funding to complete this research.
Conflicts of interest Authors declared no conflict of interest.
Data availability statement All available data are incorporated into the article.
Author contribution statement
T. T. designed the use of pulsatile flow for this patient. T. T. performed the research and analyzed the data. T. T. provided expertise in clinical data analysis. T. T. wrote the manuscript, and all authors contributed to the final version.
Ethics approval
The study was conformed by the Declaration of Helsinki and was approved by the institution ethics committee in Kitaharima Medical Center, Ono-City, Hyogo Prefecture, Japan. Medical research is a subject to ethical standards that promote and ensure respect for all human subjects and protect their health and rights. References
1. Berretta P, Patel HJ, Gleason TG, et al. IRAD experience on surgical type A acute dissection patients: results and predictors of mortality. Ann Cardiothorac Surg. 2016; 5:346--351.
2. Bayamin K, Power A, Chu MWA, Dubois L, Valdis M, Malperfusion syndrome in acute type A aortic dissection: thinking beyond the proximal repair. J Card Surg. 2022; 37:3827--3834.
3. Brown JA, Aranda-Michel E, Navid F, Serna-Gallegos D, Thoma F, Sultan I, Outcomes of emergency surgery for acute type A aortic dissection complicated by malperfusion syndrome. J Thorac Cardiovasc Surg. 2024; 167( 3): 882--892. e2.
4. Trimarchi S, Nienaber CA, Rampoldi V, Myrmel T, Suzuki T, Mehta RH, et al. Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience. J Thorac Cardiovasc Surg. 2005; 129:112--122.
5. Beck CJ, Germano E, Artis AS, Kirksey L, Smolock CJ, Lyden SP, et al. Outcomes and role of peripheral revascularization in type A aortic dissection presenting with acute lower extremity ischemia. J Vasc Surg. 2022; 75:495--503. e5.
6. Hasan I, Brown JA, Serna-Gallegos D, et al. Lower-extremity malperfusion syndrome in patients undergoing proximal aortic surgery for acute type A aortic dissection. JTCVS Open. 2023; 15:1--13.
7. Yadav I, Saifullah H, Mandal AK, et al. Cannulation strategies in type A aortic dissection: overlooked details and novel approaches, Cureus. 2023; 15( 10): e46821.
8. Lentini S, Savasta M, Ciuffreda F, et al. Treatment of malperfusion during surgery for type A aortic dissection. J Extra Corpor Technol. 2009; 41( 2): 114--118.
9. Wahid A, Shahabuddin S, Amanullah MM, et al. Direct true lumen versus conventional cannulation for acute type-A aortic dissection. J Pak Med Assoc. 2020; 70( 8): 1480--1483.
10. Haines N, Wang S, Undar A, Alkan T, Akcevin A. Clinical outcomes of pulsatile and non-pulsatile mode of perfusion, J Extra Corpor Technol. 2009; 41: P26--P29.
11. Lim CH, Nam MJ, Lee JS, Kim HJ, Kim JY, Shin HW, et al. A meta-analysis of pulmonary function with pulsatile perfusion in cardiac surgery. Artif Organs. 2015; 39:110--117.
12. Wahba A, Milojevic M, Boer C, et al. 2019 EACTS / EACTA / EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery. Eur J Cardiothorac Surg. 2020; 57( 2): 210--251.
13. O’ Neil MP, Alie R, Guo LR, Myers ML, Murkin JM, Ellis CG. Microvascular responsiveness to pulsatile and nonpulsatile flow during cardiopulmonary bypass. Ann Thorac Surg. 2018; 105( 6): 1745--1753.
14. Murphy GS, Hessel EA, Groom RC. Optimal perfusion during cardiopulmonary bypass: an evidence-based approach. Anesth Analg. 2009; 108( 5): 1394--1417.
15. Hoefeijzers MP, Ter Horst LH, Koning N, Vonk AB, Boer C, Elbers PWG. The pulsatile perfusion debate in cardiac surgery: answers from the microcirculation? J Cardiothorac Vasc Anesth. 2015; 29( 3): 761--767.
16. Takahara Y, Sudo Y, Nakano H, et al. Strategy for reduction of stroke incidence in coronary bypass patients with cerebral lesions. Early results and mid-term morbidity using pulsatile perfusion. Jpn J Thorac Cardiovasc Surg. 2000; 48:551--556.
17. Murkin JM, Martzke JS, Buchan AM, et al. A randomized study of the influence of perfusion technique and pH management strategy in 316 patients undergoing coronary artery bypass surgery. I. Mortality and cardiovascular morbidity. J Thorac Cardiovasc Surg. 1995; 110:340--348.
18. Bostancı _ I, Güner B, Kucur Tülübasß E, Demir G, Çukurova Z. Effects of pulsatile and non-pulsatile cardiopulmonary bypass techniques in coronary artery bypass grafting surgeries on cerebral perfusion. Turk J Anaesthesiol Reanim. 2024; 52( 1): 22--29.
19. Deschamps A, Hall R, Grocott H, et al. Cerebral oximetry monitoring to maintain normal cerebral oxygen saturation during high-risk cardiac surgery: a randomized controlled feasibility trial. Anesthesiology. 2016; 124( 4): 826--836.
20. Ni C, Xu T, Li N, et al. Cerebral oxygen saturation after multiple perioperative influential factors predicts the occurrence of postoperative cognitive dysfunction. BMC Anesthesiol. 2015; 15:156.
21. Brown CH. Delirium in the cardiac surgical ICU. Curr Opin Anaesthesiol. 2014; 27( 2): 117--122.
22. Eertmans W, De Deyne C, Genbrugge C, et al. Association between postoperative delirium and postoperative cerebral oxygen desaturation in older patients after cardiac surgery. Br J Anaesth. 2020; 124:146--153.