The Journal of ExtraCorporeal Technology No 56-4 | Page 19

M . Szpytma et al .: J Extra Corpor Technol 2024 , 56 , 149 – 158 157
Funding No financial funding was required for this project .
Conflicts of interest The authors declare no conflict of interest .
Data availability statement
Data use agreements restrict the distribution of raw study-related data files . Requests for data will be reviewed by the ANZCPR Steering Committee .
Authors contribution statement
Malgorzata ( Maggie ) Szpytma : Drafting of manuscript , data interpretation , input on drafts , approval of final manuscript .
Damian Gimpel : Project conception , input on drafts , approval of final manuscript . Jordan Ross : Input on drafts , approval of final manuscript . Richard F . Newland : Project conception , design and performance of data analysis , input on drafts , approval of final manuscript . Gareth Crouch : Contributed data , input on drafts , approval of final manuscript . Gregory D . Rice : Contribution and interpretation of data , input on drafts , approval of final manuscript . Jayme S . Bennetts : Contribution and interpretation of data , input on drafts , approval of final manuscript .
Robert A . Baker : Project conception and supervision , design and contributed to data analysis , drafting of manuscript , input on revisions , approval of final manuscript .
Ethics approval
Ethics approval for this audit was granted by the Southern Adelaide Clinical Human Research Ethics Committee and the South Australia Local Health Network Office for Research ( Quality Registry ID : 2265 ).
References
1 . Likosky DS , Wu X , Fitzgerald DC , Haft JW , Paone G , Romano MA , et al . ( 2020 ) Evaluating changes in del Nido cardioplegia practices in adult cardiac surgery . J Extra Corpor Technol 52 ( 3 ), 173 – 181 .
2 . Charette K ( 2012 ) Commentary on : Ninety minutes and longer : single dose myocardial protection technique utilizing the Del Nido cardioplegia solution for myocardial protection during congenital heart surgery procedures . Perfusion 27 ( 2 ), 104 .
3 . Matte GS , del Nido PJ ( 2012 ) History and use of del Nido cardioplegia solution at Boston Children ’ s Hospital . J Extra Corpor Technol 44 ( 3 ), 98 – 103 .
4 . Sanetra K , Pawlak I , Cisowski M ( 2018 ) Del Nido cardioplegia – What is the current evidence ? Kardiochir Torakochirurgia Pol 15 ( 2 ), 114 – 118 .
5 . Ad N , Holmes SD , Massimiano PS , Rongione AJ , Fornaresio LM , Fitzgerald D ( 2018 ) The use of del Nido cardioplegia in adult cardiac surgery : A prospective randomized trial . J Thorac Cardiovasc Surg 155 ( 3 ), 1011 – 1018 .
6 . Garcia-Suarez J , Garcia-Fernandez J , Martinez Lopez D , Reques L , Sanz S , Carballo D , et al . ( 2023 ) Clinical impact of del Nido cardioplegia in adult cardiac surgery : A prospective randomized trial . J Thorac Cardiovasc Surg 166 ( 5 ), 1458 – 1467 .
7 . Govindapillai A , Hua R , Rose R , Friesen CH , O ’ Blenes SB ( 2013 ) Protecting the aged heart during cardiac surgery : use of del Nido Cardioplegia provides superior functional recovery in isolated hearts . J Thorac Cardiovasc Surg 146 ( 4 ), 940 – 948 .
8 . Jung JC , Kim SI , Hwang HY , Sohn SH , Choi JW , Chung JH , et al . ( 2022 ) Serial ultrastructural evaluation of myocardial ischemic injury after infusion of del Nido Cardioplegia in the human heart . J Thorac Cardiovasc Surg 164 ( 2 ), 528 – 535 . e2 .
9 . Koda Y , Kitahara H , Nishida H , Jeevanandam V , Ota T ( 2021 ) A proposed redosing interval of del Nido cardioplegia solution in adult cardiac surgery : a propensity-matched study . Perfusion 36 ( 5 ), 463 – 469 .
10 . Chen H , Wang L , Wan L , Xiao L , Chen X ( 2021 ) Use of del Nido cardioplegia in acute aortic dissection surgery . Perfusion 36 ( 3 ), 233 – 238 .
11 . Shi H , Luo H , Qi X , Zhao H , Liu C , Chen H , et al . ( 2020 ) del Nido cardioplegia in surgery for aortic root disease : a historically controlled study . J Thorac Dis 12 ( 8 ), 4105 – 4114 .
12 . Timek T , Willekes C , Hulme O , Himelhoch B , Nadeau D , Borgman A , et al . ( 2016 ) Propensity matched analysis of del Nido cardioplegia in adult coronary artery bypass grafting : initial experience with 100 consecutive patients . Ann Thorac Surg 101 ( 6 ), 2237 – 2241 .
13 . Timek TA , Beute T , Robinson JA , Zalizadeh D , Mater R , Parker JL , et al . ( 2020 ) Del Nido cardioplegia in isolated adult coronary artery bypass surgery . J Thorac Cardiovasc Surg 160 ( 6 ), 1479 – 1485 . e5 .
14 . Mick SL , Robich MP , Houghtaling PL , Gillinov AM , Soltesz EG , Johnston DR , et al . ( 2015 ) del Nido versus Buckberg cardioplegia in adult isolated valve surgery . J Thorac Cardiovasc Surg 149 ( 2 ), 626 – 634 , discussion 34-6 .
15 . Yerebakan H , Sorabella RA , Najjar M , Castillero E , Mongero L , Beck J , et al . ( 2014 ) Del Nido cardioplegia can be safely administered in high-risk coronary artery bypass grafting surgery after acute myocardial infarction : a propensity matched comparison . J Cardiothorac Surg 9 , 141 .
16 . Sorabella RA , Akashi H , Yerebakan H , Najjar M , Mannan A , Williams MR , et al . ( 2014 ) Myocardial protection using del nido cardioplegia solution in adult reoperative aortic valve surgery . J Card Surg 29 ( 4 ), 445 – 449 .
17 . Ross JDW , Newland RF , Hamson RTJ , Rice GD , Baker RA ( 2021 ) Del Nido cardioplegia in adult cardiac surgery : analysis of myocardial protection and post-operative high-sensitivity Troponin T . ANZ J Surg 91 ( 10 ), 2192 – 2198 .
18 . Willekes H , Parker J , Neill J , Augustin G , Fanning J , Spurlock D , Murphy E , Leung S , Boeve T , Leacche M , Willekes C , Timek T ( 2024 ) Efficacy of del Nido cardioplegia in adult cardiac procedures with prolonged aortic crossclamp time . J Thorac Cardiovasc Surg 167 ( 3 ), 996 – 1007 . e4 .
19 . D ’ Angelo AM , Nemeth S , Wang C , Kossar AP , Takeda K , Takayama H , et al . ( 2022 ) Re-dosing of del Nido cardioplegia in adult cardiac surgery requiring prolonged aortic cross-clamp . Interact Cardiovasc Thorac Surg 34 ( 4 ), 556 – 563 .
20 . Chung MM , Erwin WC , Ning Y , Zhao Y , Chan C , D ’ Angelo A , et al . ( 2022 ) A novel dosing strategy of del Nido cardioplegia in aortic surgery . JTCVS Open 10 , 39 – 61 .
21 . Lin X , Jiang Y , Zhu P , Peng Q , Meng W , Zheng S ( 2022 ) The application of del Nido cardioplegia for myocardial protection in adult coronary artery bypass grafting : a cohort study . J Thorac Dis . 14 ( 1 ), 177 – 184 .
22 . Misra S , Srinivasan A , Jena SS , Bellapukonda S ( 2021 ). Myocardial protection in adult cardiac surgery with del Nido versus blood cardioplegia : a systematic review and metaanalysis . Heart Lung Circ 30 ( 5 ), 642 – 655 .