180 K . Kohlsaat et al .: J Extra Corpor Technol 2023 , 55 , 175 – 184
Figure 1 . Electrolytes , glucose , and lactate measurements throughout the perioperative period . Distribution of electrolytes , glucose , and lactate measurements are displayed as box and whisker plots for both the standard prime and PBUF cohorts . The lower and upper borders of the box represent the 25th and 75th percentiles . The middle horizontal lines represent the median . The lower and upper whiskers represent the minimum and maximum values of non-outliers , while extra dots represent outliers . It is important to note that in the panel depicting lactate values , an outlier with a value > 20 mmol / L is not shown , as it would greatly shrink the box plot by expanding the scale . Furthermore , pH for prime values was measured at a temperature of 30 ° C . pH on bypass was measured at 37 ° C ( alpha-stat ) for all cases performed at > 30 ° C . pH on bypass was measured at the target temperature ( pH-stat ) for all cases 30 ° C . For both cohorts , blue represents the first prime values , green represents the final prime values after PBUF ( the same measurements are used for the blue and green groups for the standard prime cohort ), orange represents the first CPB values after bypass initiation , and red represents the last CPB values prior to bypass cessation .
Table 4 . First CPB laboratory values .
|
Standard Prime ( n = 417 ) |
PBUF ( n = 704 ) |
P value |
pH on CPB 1 |
7.33 [ 7.29 , 7.37 ] |
7.35 [ 7.31 , 7.38 ] |
< 0.001 |
Na + ( mmol / L ) |
142 [ 141 , 144 ] |
141 [ 139 , 143 ] |
< 0.001 |
Glucose ( mg / dL ) ( n = 416 , 704 ) |
180 [ 158 , 213 ] |
154 [ 132 , 178 ] |
< 0.001 |
K + ( mmol / L ) ( n = 417 , 700 ) |
3.5 [ 3.1 , 4.0 ] |
3.3 [ 3.0 , 3.8 ] |
0.001 |
Ca ++ ( mmol / L ) ( n = 416 , 704 ) |
1.18 [ 0.99 , 1.34 ] |
1.19 [ 1.04 , 1.31 ] |
0.71 |
Lactate ( mmol / L ) ( n = 406 , 699 ) |
1.8 [ 1.4 , 2.5 ] |
1.5 [ 1.1 , 2.1 ] |
< 0.001 |
OSM ( mOsm / kg H 2 O ) ( n = 416 , 704 ) |
294 [ 290 , 298 ] |
290 [ 286 , 295 ] |
< 0.001 |
Values shown are number ( percent ) or median [ 25th , 75th percentiles ]. 1 pH on bypass was measured at 37 ° C ( alpha-stat ) for all cases performed at > 30 ° C . pH on bypass was measured at the target temperature
( pH-stat ) for all cases 30 ° C . CPB : cardiopulmonary bypass ; dL : deciliters ; kg : kilograms ; L : liters ; mg : milligrams ; mmol : millimoles ; mOsm : milliosmoles ; OSM : osmolality ; PBUF : pre-bypass ultrafiltration .