A Saturday morning practice session was staged ahead of the afternoon's qualifying session.
As all the drivers and the cars went out on to the track for the practice session, something unplanned unfortunately happened to Button.
When Button exited the tunnel he lost control of his BAR-Honda car as he scraped the side of the barrier and plummeted into the crash pad opposite the tunnel.
Button experienced a heavy crash which would see him not take part for the rest of the Grand Prix weekend.
Six years later, Button would win the 2009 Monaco Grand Prix which helped him win his first and only Driver's Championship with Brawn GP.
The 2011 F1 season was Sergio Perez's debut year by representing the Sauber team alongside his teammate Kamui Kobayashi.
The 2011 Monaco Grand Prix would be the Mexican's first go at the famous street circuit as an F1 driver.
During the qualifying sessions on the Saturday of the race weekend, on a typical warm and sunny day in Monte Carlo, Perez was on a flying lap and after exiting the tunnel - the Mexican made the same mistake as what Button did in 2003.
Jenson Button - Crash - 2003
Sergio Perez - Crash - 2011
Perez rammed into the barrier to his right while going down the slope and headed straight to the crash pad.
The impact was a nasty one and that resulted in the rookie driver to retire for the rest of the weekend.
Perez even had to resign from the following race which was the Canadian Grand Prix in Montreal.
However, the 2016 Monaco Grand Prix was a race to remember for Checo as he sealed a podium place by finishing in third.