The Fox Focus Fall/Winter 2019 | 页面 5

Fall / Winter 2019 | Research 3 “Ken’s gift stands to level up the pursuit of a revolutionary resource.” Jamie Eberling, PhD Director of Research Programs at The Michael J. Fox Foundation “The ability to detect and diagnose disease in its earliest stages would give patients answers sooner and allow researchers to develop and test early intervention or even prevention therapies,” said Jamie Eberling, PhD, Director of Research Programs at MJFF. “Ken’s gift stands to level up the pursuit of a revolutionary resource.” For many years, the Foundation has funded independent studies and organized a consortium toward an alpha-synuclein imaging agent. In 2016, MJFF announced a $2-million prize for the first team to show clinical evidence of a tracer and make it available to the research community at large. (This fall, at the Foundation’s 2019 PD Therapeutics Conference, biotechnology company AC Immune will share results from one such trial.) The Ken Griffin Alpha-synuclein Imaging Competition brings these efforts to the next level. The competition is structured to drive independent scientific teams to race to develop the synuclein tracer. The program is open now and accepting applications with the expectation of funding a total of $8.5 million to as many as three winning research teams. The team that progresses furthest in two years or less will be awarded an additional $1.5 million to continue the work and bring this game- changing tool to life. In his 2019 letter to investors, Griffin wrote: “Firms with the greatest capabilities, the deepest expertise and the most disciplined execution continue to generate significant returns, while firms that falter on these dimensions fall further and further behind.” Powered by the support of strategic philanthropists including Griffin, as well as thousands of gifts from everyday patients and families, the Foundation continues striving to achieve such returns for the Parkinson’s community.