The Catalyst Issue 18 | April 2014 | Page 24

INNOVATION | to heal patients and give them hope that will slow these diseases.” As part of the research, scientists are comparing veterans with these conditions to healthy veterans of the same era. Of particular interest are those who encountered similar hazards but appear to have no residual symptoms. Understanding vulnerability and resiliency factors for those who encounter acute psychological trauma, chemical insult, and traumatic brain injury is essential. It provides crucial insights into the pathways involved in developing long-term after-effects and clues for identifying effective treatments. Marshaling our forces The patient participants for these three research programs share one defining characteristic: they have taken on dangerous occupations for the greater good, putting themselves at great risk in service to their community or their country. The health consequences can follow multiple lifelong pathways. Some are clearly disease free; some develop a single chronic condition; a third group has a complex array of issues, which can share multiple characteristics. For example, TBI and Gulf War Illness sufferers typically experience chronic pain and cognitive difficulties, those with PTSD and TBI often experience depression, and some develop chemical dependencies. Therefore, the collaboration across disciplines among three scientists with separate and distinct expertise is a natural logical step, accelerating tangible scientific progress for their patients. Each researcher tackles the 24 THE CATALYST April 14 | sw.org topics from her own perspective, leads her own related studies, and agrees that working together produces a sum greater than its individual parts. The scientists employ neuroimaging studies, genetic tests, and clinical assessments, all with the objective of using cuttingedge science to address the urgent need for improving the health of affected veterans and emergency responders. “We have several different populations vulnerable to complex health conditions,” says Dr. Little. “I feel a significant responsibility to serve these veterans and active duty soldiers because they’re at repeated risk for injury and long-term health consequences that result from their service to our country. It’s the nature of their jobs,” she says. Dr. Steele agrees: “We all have different areas of expertise, which are all essential for addressing these complex conditions. I’m extremely excited to partner with Scott & White in this important work.” A valiant effort “We take pride in our Texas military culture, and feel a tremendous sense of gratitude,” says Dr. Little. “We’re all studying diseases you can’t see on an X-ray or identify with basic lab workups. But, as experts in our areas, coming together gives us the potential “ e’ve done a better W job of saving lives through enhanced combat trauma medicine and personal protective equipment.” —Deborah Little, PhD to do more,” she says. And will clearly impact the lives of those who serve beyond our state border. Dr. Gulliver says, “I’m in awe of the people who volunteer for our studies; first they risk their lives in the line of duty, then they put in the additional effort of meeting with us, even sometimes taking the leap of faith to try new or experimental treatments. Our participants just keep making contributions to society: in the work they do, in the time they spend, and in the risks they take, entrusting us with the detailed biological and psychological information needed to improve care for those with difficult, and sometimes still impossible, conditions to treat.” As researchers get a better understanding of the biology that explains the physical, emotional, and mental health deficits that ravage the lives of so many, veterans and first responders are finding hope knowing that, just as they’ve done for so many before, help is now on the way for them. n The investigators are pleased to have funding from federal agencies, including the National Institutes of Health, the Federal Emergency Management Agency, the Department of Defense, as well as meaningful support from Scott & White Healthcare System for Dr. Gulliver and Dr. Little and from Baylor University for Dr. Steele. More funding is needed to advance these studies. To learn more, pleas H