The Cannavist Issue Four | Page 81

Research from the University of Queensland has discovered antibacterial properties in CBD, which, scientists say, has the potential to treat MRSA and staphylococcus in the future. Outlining the findings, the Australian research team confirmed, “Cannabidiol possesses surprisingly effective activity as an antibiotic, compared to widely used antibiotics.” The study was led by Dr Mark Blaskovich at the Institute for Molecular Bioscience’s Centre for Superbug Solutions, and was co-funded by an Australian government grant scheme and CBD company Botanix Pharmaceuticals Ltd. SO, HOW DOES IT WORK? CBD contains antioxidant and anti-inflammatory properties. This we already knew. Now thanks to this fresh research, the possible antibacterial properties of our favourite cannabinoid can be explored further. This research suggests that the anti-inflammatory and antibiotic properties found in CBD work as a team when fighting bacterial infections: “The combination of inherent anti-microbial activity and potential to reduce damage caused by the inflammatory response to infections is particularly attractive.” This is because this research has displayed CBD’s potential to treat different aspects of the same infection, with just one form of medication. Bacteria kill-time, resistance induction and the effectivity of biofilm disruption, which is designed to make cell penetration more difficult, of a synthetic cannabinoid were all investigated. According to the researchers, synthetic CBD was used for this study due to its purity. (Synthetic CBD has no trace amounts of other cannabinoids, solvents as a result of extraction or compounds found naturally occurring within plant extracts, that could mislead results in biological testing.) The results showed the CBD compound disrupted the biofilm layer around bacteria, killing it rapidly, as well as proving impressive resistance rates. “Given cannabidiol’s documented anti- inflammatory effects … it is a promising new antibiotic worth further investigation.” WHY IS THIS IMPORTANT? The research was presented by Dr Blaskovich at the annual meeting of The American Society of Microbiology. Subsequently, a press release detailed: “The drug retained its activity against bacteria that have become highly resistant to other common antibiotics. Under extended exposure conditions that lead to resistance against vancomycin or daptomycin, cannabidiol did not lose effectiveness.” Vancomycin is commonly prescribed medication used to treat staphylococcus. However, with 50,000 staphylococcus associated deaths each year in the US alone, new developments in treatment are urgently needed. Dr Blaskovish added: “Given cannabidiol’s documented anti-inflammatory effects, existing safety data in humans and potential for varied delivery routes, it is a promising new antibiotic worth further investigation.” So far, this study has only been carried out in the lab, where mice tissue was analysed in petri dishes. So it is important to stress that people should not self-medicate to treat infections using CBD. While the promise in CBD-related science may show encouraging signs, always discuss your intake of CBD with your doctor, especially if you are taking other medications. The study tested the response of CBD to infections compared with established antibiotics and found that the plant extract can target and kill harmful bacteria rapidly.