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8 r C URCUMIN —T HE 21 ST C ENTURY C URE In addition, inflammation is a foundational cause of cardio- vascular disease and there is abundant evidence that curcumin is one of the most potent anti-inflammatory substances known to science. Therefore, it stands to reason that reduction of inflam- mation also reduces the risk of heart disease and stroke. Other studies suggest that curcumin may actually change the messages sent by genes that signal the body to build up those fatty deposits in the arteries. Image of arteries shows normal flow (top), constricted flow (center) and blocked artery (bottom).