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CHAPTER 4 Curcumin, Chronic Pain and Arthritis V irtually all of us experience occasional joint and back pain. With luck, it goes away with time, rest and perhaps an occa- sional ice pack. Sometimes it does not. Each year, about 30 million of us visit a doctor complaining of joint pain. Another 40 million or so visit a doctor looking for relief from back pain. Add in 1.5 million people with rheumatoid arthri- tis, 6.1 million with gout, 5 million with fibromyalgia and 1.5 mil- lion broken bones suffered every year by people with osteoporosis and you’ll see the magnitude of this painful problem. Long-term musculoskeletal pain affects your entire being. It drains your energy and contributes to chronic stress, a condition that has myriad negative side effects, including obesity, metabolic disorders, heart disease and perhaps even cancer. Chronic pain is often linked with depression. Who wouldn’t be depressed in the face of unrelenting pain? Joint pain and back pain are most often caused by deterioration of the cartilage that cushion joints (including the spaces between the vertebrae, causing back pain), causing bone to rub against bone and resulting in inflammation and pain. This can be caused by an injury, but most often, it is the result of 40, 50, 60 years or more of wear and tear on the joints. For most of us, our first remedy is to reach for aspirin, ibupro- fen or naproxen. That can be a fatal mistake. NSAIDs (non- steroidal anti-inflammatory drugs) like aspirin, ibuprofen and 17