Subscriptions - Maximum Yield Cannabis USA November/December 2020 | Page 93

Our Western minds tend to head to the gutter whenever
suppositories are mentioned. All giggling aside, the
use of plant-based suppositories is nothing new or all that
humorous. In fact, suppository molds have been found dating
back to the 12th century. Cannabis has been recognized and
used as a medicinal plant for centuries, so it only makes
sense that, like other cannabis-based medicines, cannabis
suppositories are not a new development. The ongoing
cannabis legalization movement has many cannabis patients
and enthusiasts experimenting with every delivery method
imaginable. This includes digging up some of the oldest
herbal remedy delivery techniques used by humans. Using
herbal suppositories is an ancient practice used to treat a
wide variety of ailments. Today, suppositories are used to
administer medications more effectively and efficiently,
particularly in situations where other delivery methods have
fallen short. Cannabis suppositories are quite promising
because they offer a unique delivery method to the body and
provide benefits that are not obtainable with other cannabis
delivery methods.
Cannabis Suppositories
A suppository is medicine in a solid form that is designed to
be inserted into the rectum for absorption. As the suppository
melts, the blood vessels in and around the rectum absorb
the medicine directly into the bloodstream. To some, this
may sound unpleasant, but it is arguably the most efficient
and effective route of delivery. Most cannabis-based
suppositories will begin working in 15-45 minutes; meaning
patients will not have to wait very long for relief. Cannabis
suppositories offer multiple benefits to medical marijuana
patients and are sure to be an influential part of cannabisbased
medicines in the future.
”Medicines
administered
rectally generally
have a faster onset
and a higher
bioavailability
compared
with oral
administration.“
Unique Delivery Method
Perhaps the most significant difference between using
cannabis in a suppository versus other consumption methods
is how the body processes substances through the rectum.
When smoking or eating cannabis, a fair portion of the
psychoactive components are transformed by the liver into a
more psychoactive molecule. In other words, when the liver
processes particular cannabinoids, including THC, it alters the
molecule so that when these molecules reach the brain, more
cognitive effects are experienced. This enhances the “high”
feeling experienced by many cannabis users. Cannabinoids
absorbed through the rectum are not routed through the liver
(they bypass it completely), which means the cannabinoids
go directly into the bloodstream. Bypassing the liver brings
forth two potential benefits of cannabis-based medications.
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