ADVERTORIAL
High-purity guanidine salts for diagnostics & biopharmaceuticals
With guanidine salts, the speciality chemicals sector addresses another rapidly growing segment. Guanidine hydrochloride and guanidine thiocyanate are indispensable in molecular biology applications. They are used in diagnostic kits, especially PCR tests, as reagents for nucleic acid isolation, a market that grew rapidly during the COVID-19 pandemic and remains highly important over the long term.
In addition, ultra-pure guanidine salts are applied in the purification of biologics such as monoclonal antibodies or recombinant proteins( e. g. epoetin, infliximab or ustekinumab). The ability to offer different purity grades and dosage forms( solid or liquid) makes producers flexible partners for the biopharmaceutical industry.
The strength of such product lines lies in backward integration: from raw materials to end products, all stages of production can be controlled, thereby guaranteeing the highest quality standards and reliable supply chains.
Nitriles for APIs
The pharmaceutical sector requires a wide variety of highly specialised nitrile compounds, which are used as intermediates in the synthesis of APIs. These include 4-aminobenzonitrile( for dabigatran or rilpivirine), 2-chlorobenzonitrile( for sartans or ketamine hydrochloride), and 4-chlorobenzonitrile( for itopride or letrozole). Such substances often serve as starting points for the development of vital drugs in oncology, virology or cardiology.
Specialised distillation processes achieve levels of quality and purity that are valued worldwide. Long experience in the production and handling of nitriles is necessary for a high level of trust, because pharmaceutical customers need to rely on consistent specifications.
Sales statement
“ Our consistent focus on high-margin speciality chemicals continues to pay off despite the ongoing challenging conditions, says Andreas Niedermaier, CEO of Alzchem Group, with respect to Q1 and Q2 2025.“ The strong increase in sales and, above all, earnings in the Speciality Chemicals segment shows that our strategic focus on future-oriented, high-growth niche markets is having a lasting effect. The noticeable upturn in demand for highly specialised products despite a difficult overall industry environment is particularly encouraging – a clear signal of our high level of innovation and customer focus.”
Contract synthesis: Customised services for complex requirements
Another central pillar of the speciality chemicals industry is contract synthesis. Modern multi-purpose facilities allow the production of tailor-made organic compounds for customers – from kilogram-scale laboratory production to tonne-scale commercial manufacturing.
Services range from developing suitable synthesis routes and process optimisation to scale-up and industrial-scale production. Customers benefit from a combination of technical expertise, modern equipment, and experienced teams of chemists and engineers.
The advantages are clear: companies lacking their own resources or capacities can access high-quality production services in a costefficient manner while remaining flexible and able to adjust capacity as needed. Particularly in the pharmaceutical sector, maximum purity, absolute reliability and comprehensive intellectual property protection are required.
Sustainability, safety & responsibility
Pharmaceutical customers expect not only the best quality, but also increasingly want sustainable production. The speciality chemicals industry meets these requirements through consistent environmental responsibility. Integrated networks ensure optimal use of raw materials, reduce emissions, and increase energy efficiency. This is complemented by extensive safety initiatives, regular incident analyses and corporate cultures that focus on health, safety and environmental awareness.
Outlook
Alzchem Group impressively demonstrates how a traditional chemical company can assert and expand its role in a changing pharmaceutical industry through innovation and customer focus. The company offers a uniquely broad portfolio that includes cyanamide, DCD, Bioselect * guanidine salts, Nitralz * nitriles, thiourea and many more.
With contract synthesis, the company offers individual services for customers who require special syntheses or flexible production capacities. Customers benefit from‘ Made in Germany’ quality, an integrated production network and a strategic focus that is equally committed to sustainability and future viability. Alzchem creates a complete package ranging from classic basic chemicals to state-of-the-art speciality applications, always with a focus on reliability, innovation, and sustainability. ●
*- Bioselect and NITRALZ are registered trademarks of Alzchem
Alzchem Group
k + 49 8621 86 2914 J specialitychemicals @ alzchem. com j www. alzchem. com
NOV / DEC 2025 SPECCHEMONLINE. COM
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