REGULATION & COMPLIANCE standards with national hazard classes and labelling conventions not aligned with GHS.
Decree 57 / 2019 has transitioned from implementation to active enforcement. Two national chemical inventories have been published, serving as official references for determining‘ new substance, status. Manufacturers and importers must provide mandatory pre-market notifications for unlisted hazardous substances and comply with biennial reporting obligations, with the next deadline set for 30 August 2026.
The first notification cycle for hazardous, industrial-use substances took place from February to September 2024, resulting in Resolution 7595 / 2024, which established Chile’ s first national chemical inventory with approximately 850 notified substances. Any substance not listed is deemed new and must be notified before manufacture or import.
The second cycle, covering hazardous non‐industrial use substances, ran from February to August 2025, culminating in Resolution 9425 / 2025, which listed 11 substances commonly used in household cleaners, paints and fragrances. Unlisted substances in this category also require notification before market placement. The first biennial update for industrial use notifications is due by 30 August 2026, followed by new notification windows for hazardous substances in industrialuse mixtures( February-August 2027) and non‐industrial use mixtures( February-August 2029).
Foreign manufacturers cannot submit notifications directly under Decree 57 / 2019. Only Chilean importers are obligated to notify, requiring strong supplier collaboration. The decree does not provide for any role similar to the Only Representative.
Colombia: Decree 1630 / 2021
Before Decree 1630 / 2021, Colombia regulated chemical substances through multiple, uncoordinated sectoral rules covering the environment, occupational safety, transport, pesticides and hazardous waste. These focused on specific uses, activities or products rather than on industrial chemicals as a group.
No single integrated national system combined an inventory of industrial substances with general notification or registration duties, nor any horizontal mechanism to prioritise substances and require systematic risk assessments and risk‐management programmes across their life cycle. This increased the risk of inconsistent control, blind spots and delayed action on hazardous substances, because authorities lacked a unified view of which industrial chemicals were in use, in what quantities and with which risks.
Decree 1630 / 2021 has also moved from implementation to active enforcement, completing the first full regulatory cycle for hazardous industrial substances. The first national chemical inventory was published in November 2025, listing roughly 4,500 hazardous industrial substances based on registrations submitted for substances produced or imported in quantities of ≥100 kg / year between 2021 and 2023, including substance identity, annual volumes, GHS classification and uses. Companies that registered 2021 – 2023 data were required to update their submitted data with 2024 volumes and relevant changes by 30 September 2025, a deadline also applying to late registrants who had to register substances as‘ new’ after missing the original 30 May 2025 cut‐off.
Following this first cycle, any hazardous industrial substance manufactured or imported that does not appear in the published inventory is now treated as‘ new’ and subject to pre‐market notification once production or import reaches 100 kg / year. Companies must notify within six months of exceeding that threshold, indicate when it was crossed, confirm whether the substance meets prioritisation criteria and, where applicable, provide a health and environmental risk assessment. The detailed resolution describing the risk assessment procedure has not yet been formally published.
Foreign manufacturers cannot submit notifications directly under Decree 1630 / 2021. However, they may appoint an Exclusive Representative from Abroad( Representante Exclusivo del Extranjero, REE) to safeguard sensitive substance information. This mechanism enables companies to maintain information confidentiality while complying with disclosure requirements.
Peru’ s new approach
Peru historically regulated chemical substances through a patchwork of sector‐specific rules managed separately by environmental, health, labour, agriculture, mining and transport authorities, each focusing on particular uses, activities or product groups rather than on industrial substances as a whole.
Controls addressed obvious hazards in specific contexts( pesticides, industrial emissions, occupational exposure) but lacked a central registry, systematic volume‐based reporting or a unified mechanism to identify which chemicals were on the market, in what quantities and with what aggregated risks.
This fragmented approach increased the risk of inconsistent oversight, regulatory gaps and slow reaction to emerging hazards, because authorities had limited visibility of the full chemical‘ universe’ in circulation and could not easily prioritise substances for detailed risk assessment and coordinated risk‐reduction measures.
Peru’ s chemical management framework under Legislative Decree 1570 / 2023 remains largely in a transitional and preparatory phase. The key implementing regulation has not yet been formally adopted, and the national registry( RENASQ) is not operational, meaning companies lack a functioning legal and technical mechanism to register substances or fully comply with future system requirements.
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