COSMETICS & PERSONAL CARE into its effects on a wide range of microorganisms showed an ability to inhibit microbial growth , greater than that of its synthetic analogues , 1,3-BD and 1,3-PD . The addition of 2,3-BD to a cosmetic formulation is therefore likely to act as a preservative booster , improving the efficacy of the preservative system .
In vitro studies of the effect of 2,3-BD on inflammation markers , using RAW 264.7 cells ( a common method to test bioactivity ), showed significant reduction in the expression of TNF-α and IL-6 at levels between 0.1 % and 1 %. A clear dose-response relationship was noted . 2,3-BD in formulation at levels above 0.1 % is therefore likely to offer some degree of anti-inflammatory action and / or to reduce erythema .
Conclusions
Cosmetic formulators like to look to natural systems for inspiration . Both they and consumers value natural and sustainable ingredients , while a high level of human safety and minimal environmental impact are essential for cosmetic use . 2,3-BD is a substance with demonstrable benefits in nature , in terms of helping plants to survive drought conditions , and in contributing to disease resistance .
GreenDiol , which Summit Cosmetics distributes in Europe , uses the same microbial process found in nature to provide a cosmetic ingredient that meets the demands for naturality ( certified natural and organic according to COSMOS ), performance , and consumer acceptability ( vegan and CFI-certified ).
It can also bring an excellent skin feel , with high hydration , and enhanced skin barrier function , evidenced by reduced TEWL . Additional benefits suggested include reduction of erythema and preservative boosting . ●
John Hibbs
PRINCIPAL
ARGUS CONSULTING k + 44 7868 216013 J john . hibbs @ argus-consulting . co . uk j www . summitcosmetics-europe . com
References 1 : European Food Safety Authority Journal , 2004 , 166 , 1-44 2 : B . Jiang & Z . Zhang , Molecules , 2010 , 15 ( 12 ), 9184 – 9196 3 : M . D . Alessandro , M . Erb , J . Ton , A . Brandenburg , D . Karlen , J . Kopfi & T . C . J . Turlings , Plant , Cell , Environment , 2014 , 37 , 813-826
2,3-BD can be sourced from biomass like sugarcane
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