Speciality Chemicals Magazine MAR / APR 2023 | Page 33

COSMETICS & PERSONAL CARE

processes that lead to the oxidation of major macromolecules ( e . g ., lipids , proteins and deoxyribonucleic acids ), to impact the quality of the skin and hair . 5 ^- 9 Here , we have demonstrated that exposome stress can induce severe damage of human skin , scalp and hair .

Exposome-induced stress damage may cause dysfunction to the skin barrier , the body ’ s first line of defence to external damage . This may lead to

an increase of trans-epidermal water loss , which may make the skin more susceptible and more vulnerable to subsequent exposures to external aggressors . It can also lead to reductions in hair vitality and cause cuticle damage , which allows moisture to pass through and swell the hair strands , leading to hair frizz .

Xpozuki Biotech Ingredient offers a new way to protect against exposome

Figure 5 - Variation in hair frizz ( above ) & hair volume ( below ) after 14 days of treatment with 2 % natural active ingredient

Notes : (** p < 0.01 v . initial time ) v . placebo . Wilcoxon test used after checking the normality distributions by a Shapiro-Wilk test . ( b ) Data shown as mean increase including statistical significance : l . s . < 0.01 v . initial time damage . In vitro , it can protect skin and scalp cell viability and repair the damage after exposome stress damage . It also protects the hair fibre from protein carbonylation and lipid peroxidation .

In vivo , Xpozuki Biotech Ingredient resulted in an improved skin tone evenness and skin texture homogeneity , decreasing exposome stress damage to the skin . Furthermore , application to the hair as a leave-on serum provides a multifunctional effect , improving frizz and volume control on multi-ethnic hair types .

Xpozuki Biotech Ingredient is an all-in-one product that protects all types of skin , scalp and hair against the exposome , including the combined effect of UV radiation , air pollution , greenhouse stress and pollen . It is suitable for use in leave-on and rinseoff cosmetic applications . ●

* - Also contributing to this article were Ramón Subirós , Sandra Méndez , Albert Soley , Gemma Mola , Núria Almiñana and Raquel Delgado ** - Xpozuki biotech ingredient is a registered trademark of Lubrizol Life Science Beauty

Dr Bianca McCarthy

GLOBAL MARKETING MANAGER

LUBRIZOL LIFE SCIENCE - BEAUTY k + 34 936 388 000 J lls . beauty @ lubrizol . com j https :// lubrizol . com / personal-care

MAR / APR 2023 SPECCHEMONLINE . COM

33