Soltalk January 2019 | Page 44

Doctor’s notes Dr Rik Heymans is a general practitioner in Nerja and writes on developments in the world of medicine Gout and Multivitamin Outcomes Study (COSMOS) will help determine whether concentrated cocoa extract can help reduce heart disease and stroke and whether commonly used multivitamin supplements can help reduce the risk for cancer, particularly in older women. It must be emphasized that the cocoa supplement to be studied is a highly concentrated extract of cocoa flavanols. This is, unfortunately, not a study about eating chocolate! It is important to differentiate between cacao, cocoa, and chocolate. Gout is a disease which is generally associated with a good lifestyle: rich and abundant foods, fowl, venison, shellfish and cheese to name but a few, swallowed down with a good wine, or liquor to top it all off. In my practice I see quite a lot of patients with this - to put it mildly - discomforting condition. The well-known and praised Mediterranean Diet, which is so beneficial for the heart, is however a main factor in people presenting with gout. And usually patient shrug it off, saying, “it is only gout”, and assume some or other pain relief will be enough to take care of it. However, these annoying crystals also affect the rest of the body. A newly published study adds more proof that gout should be managed like a chronic disease, using a treat-to-target approach to uric acid levels. The researchers looked at a cohort of almost 1200 patients attending a gout clinic between 1992 and 2017. Of this cohort, 92% of the patients were men with a mean age of 60. The men had gout for about 7 years and averaged three to four flares per year. The study showed that the patients whose serum uric acid levels were greater than 6 mg/dL were twice as likely to die prematurely compared with those whose levels were below 6 mg/dL. The raw seeds obtained from the Theobroma cacao tree are referred to as cacao. The seeds of the cacao tree are rich in a subclass of polyphenol antioxidants known as flavonoids, specifically the flavanols catechin and epicatechin. Once these seeds are processed by grinding or roasting them, the product becomes cocoa. Further processing and the addition of multiple other ingredients, including sugar and fat, result in the solid edible product we call chocolate. The medicinal use of cocoa has a long history dating back almost 500 years, when Hernán Cortés first encountered the drink in Mesoamerica. Even before Cortés, Mayans and Aztecs took beans from the cacao tree and made a drink they called "xocoatl." Aztec Indian legend relates that cacao seeds were brought from Paradise, and that wisdom and power came from eating the fruit of the cacao tree. Optimizing uric acid levels has long been a goal in gout management - in order to reduce long-term morbidity, including cardiovascular and chronic kidney disease. The uric acid crystals affect the kidneys and this then affects the rest of the body, leading to a decreased life expectancy. In light of studies suggesting that flavanol-rich chocolate may confer cardiovascular benefits, should we consider cocoa to be a cardiovascular nutraceutical? To the contrary, and important warnings are in order. During the conventional chocolate manufacturing process from fresh cocoa seeds to the final product, the concentration of flavanols is markedly reduced. And many other products are added. Finally, the high caloric load of commercially available chocolate (about 500 kcal/100 g) may cause weight gain, which is itself a risk factor for hypertension, dyslipidemia, and diabetes. Chocolate For as long as one can remember, chocolate has been considered as a "no-no" for anyone trying to lose weight, or indeed for anyone simply trying to live healthy. So what underlies the latest hype about chocolate's health benefits? Is there any truth to it? Chocolate and its ostensible preventive effects on cardiovascular disease (CVD) are being investigated in a study conducted by medical institutions and organizations of renown: the Brigham and Women's Hospital, the Fred Hutchinson Cancer Research Center, and the Women's Health Initiative. Started earlier this year, the 5-year, large-scale randomized controlled trial is testing the effect of a concentrated cocoa extract and multivitamin supplements in reducing the risks for CVD and cancer. The Cocoa Supplement While we await the results of this COSMOS study, the scientific recommendation is to rely on exercise and diet to enhance cardiovascular health. If you are a "chocoholic," it is fine to eat dark chocolate, but at present solely for enjoyment—not yet on the pretence that we are indulging for medicinal benefits. © Dr RIK HEYMANS c/ Angustias 24, Nerja. Tel: 95 252 6775 42