Senwes Scenario December 2018 / January 2019 | Page 23

AGRICULTURAL presented only with a percentage of ani- mals although all the animals have been exposed to the infection. WHAT IS THE NUTRITIONAL REQUIREMENTS OF STRESSED ANIMALS? Acute (immediate) or prolonged (two to seven days) stress makes animals more susceptible to disease. Stressful stimuli in cattle include handling, transport, physical trauma, fatigue, fasting, and unfamiliar environment. Increasing levels of hor- mones like cortisol, epinephrine, norepi- nephrine, aldosterone, beta-endorphin, and encephalin are released during stress. These induce hormonal responses which control and alter animal metabolism hor- mones, suppress the immune system by depleting nutrients critical to an effective immune response. Metabolic pathways shift from anabolic processes (growth) to primarily catabolic (tissue breakdown of proteins and fat). WHAT IS THE EFFECTS OF DISEASE ON NUTRITIONAL STATUS? Infection results in a complex array of metabolic responses which affect the nutritional status of the animal. Feed intake decreases more than 50% in cattle with respiratory disease and fever, and takes 10 to 14 days to return to normal. During this time, requirements of virtually all nutrients increase, even though nutrients are deflected from growth to immunity. Proteins must be synthesized for the immune response, development and reso- lution of fever, and repair of cell and tissue damage. Body proteins are broken down to provide energy and amino acids for the immune system. Losses of important minerals such as magnesium, potassium, phosphate, and zinc are also increased. The major extracellular electrolytes, sodium and chloride, are influenced by hormonal changes. Urinary excretion of salt may increase during the onset of infec- tion, and may lead to dehydration. The kidneys may then begin to retain body salt and water. Diarrhoea can result in substan- tial direct faecal losses of sodium, chloride, bicarbonate and potassium. The immune system appears to have priority for nutrients over growth. Immune activation is costly. Resources devoted to immune activation cannot be used for growth. As a result, any immune response will depress growth rate and feed efficien- 22 SENWES SCENARIO | TECHNOLOGY & INNOVATION 2018 21