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Sciatica – Why You Have Been Treating It Wrong © SciaticaSOS.com that results into a herniated disc. The leaked disc tissues contain an acidic chemical that is irritating and results into nerve inflammation and pain. Lumbar spinal stenosis: This is a nerve compression disorder that’s mostly common with older people and results into the narrowing of the spinal canal. The condition may be caused by the overgrowth of soft tissue or a bulging disc that exerts pressure on the nerve roots resulting into sciatica. Piriformis syndrome: This condition occurs when the piriformis muscle, a small muscle that’s found deep in the buttocks tightens. It can exert pressure and irritate the sciatic nerve resulting into pain. Isthmic spondylolisthesis: This condition is caused by a slip of one vertebra resulting in misalignment. When there’s fracture or disc space collapse, where one vertebral body slips over the one below due to fracture on the bone connecting the two joints, the root nerve can easily get triggered and cause sciatica. The fracture can be caused by stress on the bone. Trauma: External pressure on the spinal nerve roots resulting from accidents, falling, or any other external force to the lumber has the potential of causing compression to the nerves that can also lead to sciatica. 3