School of Science Capabilities | Page 36

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Bioinformatics- The Future of Science Research
Dr Wee Wei Yee wee. weiyee @ monash. edu
Lecturer
Expertise Expertise
Whole genome analysis Public health Microbial metagenomics Education Single cell RNA sequencing Financial statistics analysis
Achievement / Award The Dean’ s Award for Innovation in Learning and
Teaching( 2024) PVC’ s Award for Excellence in
Education( 2024) Gold Medal- International Invention, Innovation, and Technology Exhibition( 2020)
I use bioinformatics to analyse whole genome sequencing data to generate annotated genome assemblies and identify genes. I also conduct comparative genomic analysis that reveal evolutionary and functional insights and identify mutations and antimicrobial resistance genes, to transform complex genomic data into actionable biological knowledge.
My interest lies in the exploration of microbial communities in environments such as the gut, soil and oceans. I routinely conduct analysis of 16S rRNA, shotgun metagenomics, and meta transcriptomics data to identify microbial species, their abundance and functional roles. Insights from these studies have translational applications in health, agriculture and environmental sciences.
I analyse RNA sequencing data to study differential gene expression to capture the overall transcriptome in different cell populations and tissues in health or disease and other conditions, revealing global expression patterns.
The findings from these studies are used in research on cancer, autoimmune diseases and developmental biology, helping us understand the roles of specific genes in biological and metabolic processes.
Bioinformatics is an integral part of scientific endeavour in present times
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