SAEVA Proceedings 2016 | Page 174

  achieve the angle and support the foot that may tend to land unevenly, particularly in show horses. In a recent study however, we found that neither the lateral extension shoe nor the rolled toe shoe with elevated heels had a consistent effect on the position of the point of zero moment (point of force) of the foot during stance, on the orientation of the hindlimbs during flight nor on the clinical lameness of these horses, thereby questioning their efficacy. Anti-inflammatory medication Anti-inflammatory therapy is required to resolve or control the pain resulting in lameness. Generally, the best plan is to do the minimum required to keep the horse effectively in work, because more treatment will probably be required eventually. Each horse is different and requires discovery of an effective treatment schedule. A starting point includes systemic phenylbutazone (2.2 mg/kg, BID), which can be continued for an extended period of time in most horses or given only when the horse is worked. Intra-articular corticosteroids Intra-articular medication with corticosteroids (40-80 mg methylprednisolone, 6-12 mg bethamethasone or 6-12 mg triamcinolone acetonide) is more predictably successful in rendering horses sound, although reported success rates vary from 35% to 70% of horses injected being improved (Labens et al. 2007; Byam-Cook et al. 2009). Medical treatment is best selected for those horses that have minimal radiological changes and combined with a program of controlled walking together with alterations of the shoeing. Therapeutic concentrations of methylprednisolone have been measured in both the TMT and DIT joints following injection of the TMT joint only (Serena et al. 2005). However, clinical impressions suggest strongly that both joints (TMTJ + DITJ) must be injected concurrently for optimal effect and to avoid unexpected treatment failures. When the horse responds poorly to initial treatment with intra-articular steroids, a second injection 3 to 4 weeks later may be more effective. Using triamcinolone (6 mg/ joint) for the first injection and scheduling a second injection with 80 mg methylprednisolone makes sense in horses for which long-term pain control is needed. A period of reduced activity after medication usually improves the result; the rest period has subjectively varied from 5 to 14 days in show horses. Tiludronate Tiludronate inhibits osteoclast activity and has been used in horses with distal tarsal pain. In a limited double-blind clinical trial of 8 horses with lameness confirmed to originate in the distal tarsal joints given 1 or 2 single IV doses, 1 horse improved (Dyson 2004). More recently, a larger study using 86 horses showed an average improvement of 2 (out of 10) lameness grades in horses treated with an infusion of tiludronate and a controlled exercise regime, which was significantly better than the improvement seen in horses in the placebo group (Gough et al. 2010). However, it was considered difficult to separate the effect of tiludronate from the effect of the controlled exercise regime in improving lameness. Clodronate, a new bis-phosphonate has become 15-­‐18  February  2016      East  London  Convention  Centre,  East  London,  South  Africa     173