SAEVA Proceedings 2016 | Page 201

  Aspartate amino transferase (AST) – increased as for CK, also with liver disease (often too acutely fatal in neonates) Bile acids-elevated in first week of life. Useful to assess liver function. Urea – elevated with dehydration/haemoconcentration, (ruptured bladder in neonate) and abnormal renal function. uroperitoneum Creatinine – Can be elevated in the first 48 hours of life and not reflect renal pathology. Premature placental separation will also cause increase in creatinine. If azotaemia persists, serum electrolytes should be examined. Comparisons of serum and peritoneal fluid levels are useful in diagnosing uroperitoneum (peritoneal fluid concentration 1.5-2 x serum/plasma concentration). Glucose – Hypoglycaemia (<4mmol/l) most likely indicates inadequate milk intake and is an important complication of any disease process putting the foal off suck. If samples are going to an external lab then they must be collected into fluoride oxalate tubes or be tested ‘stable side’ using a portable glucometer (available from any chemist). Lactate –Lactate can be measured by some labs and also with several ‘stable side’ machines. Lactate represents the degree of anaerobic metabolism that has occurred and is an excellent guide to prognosis, not only the initial value, but how lactate values respond to your initial treatment. Electrolytes Significant electrolyte disturbances can occur with renal dysfunction, bladder rupture and diarrhoea. Normal ranges are similar to adult levels and values should be monitored if possible in serious disease and in all foals showing seizure activity. Urinalysis Foals produce large volumes of dilute urine SG 1.001-1.015. Is Is more acidic than adult urine and may contain proteins during the first 24-36 hours of life due to colostrum intake and excretion of these proteins. Faecal analysis Faeces can be collected for culture, clostridial enterotoxin assessment, presence of cryptosprodia and rota virus (and possibly Corona) antigen detection. Diagnostic Imaging With the now widely available portable DR systems and small portable yet high quality ultrasound machines, it is relatively easy to perform radiographic and ultrasonographic survey evaluations on the farm. 15-­‐18  February  2016      East  London  Convention  Centre,  East  London,  South  Africa     200