Revista de Medicina Desportiva (English) May 2018 - Page 15

with high load impact. Actually, 27 studies show reduction on pain and of symptoms of osteoarthritis when taking glucosamine sulfate. The effective dose for the adult is 1500mg per day per os. However, in the adolescent practitioner, it can be used “off-label “ (after 16 years), with doses between 750 to 1500mg. • Supplementation with Chondroi- tin 36,37 It is a supplement widely used in association with glucosamine or isolated for reduction of symptoms in the osteochondral pathology. The dose used in the adult is 500 to 1200mg per day, orally, not being explicitly advised in children. How- ever, since this drug is often associ- ated with glucosamine, it can be used off-label on teenagers after the age of 16 with moderate doses. Hyaluronic acid and platelet-rich plasma (PRP) 38-42 Viscosupplementation is widely used to improve the joint biomechanics function and reduce pain through its potential physical therapeutic properties and applied chemical sub- stances. The anti-inflammatory, scar- ring and lubrication power are some points stated. However, although widely studied and compared, the evidence is controversial and often only moderate. Moreover, it has only been studied in joints already with obvious lesions (notably with osteo- arthritis) and in the adult popula- tion. There are no recommendations for their use in the age of 18 years. Using PRP in this group of practition- ers, children and adolescents has no evidence or any kind of recom- mendation. Its use off-label assumes experimental characteristics. Other supplements In this group of athletes, no other supplement has showed scientific evidence in the therapeutics and prevention of cartilage lesions, so it is not recommended to use it. Conclusion The pathology of cartilage is becom- ing increasingly frequent in children and adolescents for several reasons. However, the clinical investigation of this pathology, in this population group, is very limited and usually of low evidence. 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