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Table of Contents :
1 . The Case for Innovation 6 2 . Clinical and Commercial Landscape 10 3 . Assessment of Pipeline Product Innovation 25 4 . Type 2 Diabetes Mellitus Signaling Network , Disease Causation and Innovation Alignment
48 5 . First-in-Class Target and Pipeline Program Evaluation 54 6 . Strategic Consolidations 67
List of Tables :
Table 1 : Type 2 Diabetes Mellitus , Global , Related Indications of T2DM First-in-Class Products , 2016 49 Table 2 : Type 2 Diabetes Mellitus , Global , Pipeline Programs Targeting Insulin Receptor Substrate 1 , 2016 55 Table 3 : Type 2 Diabetes Mellitus , Global , Key Features of Insulin Receptor Substrate 1 , 2016 55 Table 4 : Type 2 Diabetes Mellitus , Global , Pipeline Programs Targeting Insulin Receptor Substrate 2 , 2016 55 Table 5 : Type 2 Diabetes Mellitus , Global , Key Features of Insulin Receptor Substrate 2 , 2016 55 Table 6 : Type 2 Diabetes Mellitus , Global , Pipeline Programs Targeting G-Protein Coupled Receptor Kinase 5 , 2016 56 Table 7 : Type 2 Diabetes Mellitus , Global , Key Features of G-Protein Coupled Receptor Kinase 5 , 2016 57 Table 8 : Type 2 Diabetes Mellitus , Global , Pipeline Programs Targeting Type 2 Angiotensin II Receptor , 2016 58 Table 9 : Type 2 Diabetes Mellitus , Global , Key Features of Type 2 Angiotensin II Receptor , 2016 58 Table 10 : Type 2 Diabetes Mellitus , Global Pipeline Programs Targeting Islet Amyloid Polypeptide , 2016 59 Table 11 : Type 2 Diabetes Mellitus , Global , Key Features of Islet Amyloid Polypeptide , 2016 59 Table 12 : Type 2 Diabetes Mellitus , Global , Pipeline Programs Targeting Nacht LRR and PYD Domains Containing Protein 3 , 2016 60 Table 13 : Type 2 Diabetes Mellitus , Global , Key Features of Nacht LRR and PYD Domains Containing Protein 3 , 2016 61
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