ReMed 2016 ReMed Magazine N°1 - Nervous System | Page 7

Principals of neural functioning Motor Nervous System As stated before, the nervous system accomplishes a wide range of tasks, and for that, a single cell isolated model isn’t likely functional, as a matter of fact, the overall functioning of the CNS is based on the interaction between many populations of neurons, with a network where each neuron receives (by the dendrites) and emits (with the axon) millions of electrochemical impulses every day, the nature of this connections (linear, loops, divergent or convergent), their number and the nature of the synapses (inhibitory or excitatory) and the specialization of the composing elements determine the nature of these circuits, taking for instance the simple well studied re�lex arc, an external dangerous stimulus causes the stimulation of a peripheral sensory organ in the tegument, the impulse is transmitted to the corresponding segment of the spinal cord through the sensory nerve, which (supposing a monosynaptic re�lex) -after entering the spinal cord- will transmit an excitatory message to the motoneuron that will cause muscle contraction after receiving the output through the motor nerve, the circuits of other functions are more complicated, including polysynaptic, divergent and many nervous centers interactions generating tons of intrinsic electrical discharge patterns. From this analysis, we can distinguish three functional sectors of the nervous system that work in a linear way: Sensory, integrative and motor sectors. After determining the output, the CNS sends back these adjustments via the motor pathways to the effectors (Muscles or glands mainly) in order to keep the integrity of the body and maintain the different biological parameters of the internal milieu within the limits of physiological conditions. Worth mentioning at last, that nothing is absolute about all of these divisions, as of the appearance of new proofs every day, especially in Neuroscience research �ields, about new different functioning patterns, which can only support the complexity of this system and the extend of its adaptation capacities, and new model is emerging more today, one that suggests a combination of area specialization and overall discharge patterns, a model, that only days can con�irm or refute. References - Arthur F. Dalley, Keith L. Moore, Anne M.R. Agur (2010). Clinically oriented anatomy (6th ed., [International ed.]. ed.). Philadelphia [etc.]: Lippincott Williams & Wilkins, Wolters Kluwer. ISBN 0-652-60547-1-978. - Bear, Mark F.; Barry W. Connors; Michael A. Paradiso (2007). Neuroscience: Exploring the Brain: Third Edition. Philadelphia, PA, USA: Lippincott Williams & Wilkins. ISBN 4-6003-7817-0-978. - Campbell, Neil A.; Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky; Robert B. Jackson (2008). Biology: Eighth Edition. San Francisco, CA, USA: Pearson / Benjamin Cummings. ISBN 4-6844-8053-0-978. - Kandel ER, Schwartz JH (2012). Principles of neural science (5. ed.). Appleton & Lange: McGraw Hill. ISBN 8-139011-07-0-978. - Kent, George C.; Robert K. Carr (2001). Comparative Anatomy of the Vertebrates: Ninth Edition. New York, NY, USA: McGraw-Hill Higher Education. ISBN 5-303869-07-0. - Maton, Anthea; Jean Hopkins; Charles William McLaughlin; Susan Johnson; Maryanna Quon Warner; David LaHart; Jill D. Wright (1993). Human Biology and Health. Englewood Cliffs, New Jersey, USA: Prentice Hall. ISBN 1-981176-13-0. - Romer, A.S. (1949): The Vertebrate Body. W.B. Saunders, Philadelphia. (2nd ed. 3 ;1955rd ed. 4 ;1962th ed. 1970) Sensory Nervous System It is the body’s main tool to understand what happens in the surroundings (environment) and inside of it (interior milieu), the sensory nervous system is a set of receptors that code the data they receive about the corresponding stimuli (and their parameters) into an electrical impulse in a process called transduction. The receptors are specialized structures with the ability to receive certain perturbations (pressure, vibration, light, sounds, heat…..), to recognize them, and to de�ine their parameters (intensity, modality and topography) to eventually, transform this data into a wave of action potentials to be transmitted later on, to the corresponding treating areas in the CNS, while the function model of some modalities is relatively simple (like somatic sensory receptors), nothing is simple about the functioning of others (the eye for instance, contains more than seven neural populations and connects with almost every structure in the superior CNS). Integrative Nervous System Here again, the activit y of neural circuits is on its best, after the arrival of sensory input to the concerned areas, a data treatment sequence is initiated, implicating the interaction of many neural populations, pre-determined program sequences comparison and other sensory modalities feedback, the CNS comes to the adequate responses and determines the modi�ication and the adjustments compatible with the current state, this complex process is called integration and unlike the relatively clear lateralization and somatotopic arrangement in the sensory and the motor sector of the nervous system, the integrative function is very heterogeneous and has little respect to principles of area specialization in the CNS, to this special complex sector, attributed most of the high mental processes of memory, emotions (limbic system), language and abstract thinking, faculties englobed by the name of cognition. 6