ReMed 2016 ReMed Magazine N°1 - Nervous System | Page 22

I believe that most of you are familiar with John Nash’s battle with schizophrenia. (For those who are not, I recommend watching “A beautiful mind“). The Nobel-prize-winning mathematician who has successfully but not easily reintegrated himself back into reality. His story, as exceptional and contradictory as it is, remains indeed a positive and beautiful model in its outcome and shows that a long way is still ahead in order to make more similar results. Bibliography: • Rang, H. P., and M. Maureen. Dale. Rang and Dale's Pharmacology. Edinburgh: Elsevier/Churchill Livingstone, 2012. • Laura WeissRoberts - Jinger G.Hoop - Thomas W.Heinrich - Wolters Kluwer Health/Lippincott Williams & Wilkins - 2010 • Joshua T. Kantrowitz, MD Daniel C. Javitt, MD, PhD. "Glutamate: New Hope for Schizophrenia Treatment. Research on Glutamatergic Dyfunction May Lead to Therapies Targeting Negative and Cognitive Symptoms." Current Psychiatry. Apr. 2011. Web • Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR. Arlington, VA, American Psychiatric association, 2013. • http://www.schizophrenia.com/ Living as a schizophrenic is a great burden because Many challenges still exist and are present especially on a social level. The attempt to integrate the patient into society remains a main one. It requires not only a supportive and encouraging family, but also a more understanding environment. For many years, the only way to deal with this disease was to con�ine these patients to asylums, where they were treated not in the most humane way. Moreover, the �irst-line therapy at the time consisted of electroshock therapy, psychosurgery (frontal lobotomy), and insulin coma. These therapies were extremely controversial because they can cause permanent damage and sometimes lead to death, which is extremely unfortunate given that schizophrenia is an illness that mainly touches young adults. It is true that the discovery of neuroleptics has led to a drastic decline in the number of schizophrenics detained in asylums, and rendered the use of those extremely disabling measures mentioned above a thing of the past. This being said, the pharmacological treatment of schizophrenia did not make it more socially acceptable and there still is fear and misunderstanding related to it. Sadly, this prejudice has been observed in the medical �ield, and has led to a bad follow-up of many schizophrenics for their non-psychiatric conditions. The most prominent one being cardiovascular disease for it remains the �irst cause of death among them. It is, in fact, the reason why a schizophrenic person lives thirty years less than the average individual. 21