RACA Journal August 2020 | Page 39

Getting Technical CHARLES NICOLSON Charles Nicolson has a physics and chemistry degree from Natal University which he subsequently put to good use by applying speciality chemicals in mining and industrial processes where water is a major factor. This created an enduring interest in water technology, a passion that expanded to the HVAC industry in 1984 when he joined BHT Water Treatment. Since then, water technology in HVAC water circuits has continued to be an abiding interest. VIRUSES. WHAT ARE THEY? By Charles Nicolson This article about viruses was written in February this year before the Corona ID -19 virus which had started in China exploded into the current global pandemic. In recent years nothing has grabbed the attention of the populace world-wide as much as the escalating mortality toll caused by the onslaught of this virus as it continued to spread. News media have concentrated intensely on reporting infections, rising numbers of deaths (and recoveries) and the dedication of courageous and heroic medical and health workers. However, understandably there has been virtually no information as yet regarding the basic question: what is a virus? According to microbiologists, viruses are by far the most abundant biological entities on earth, outnumbering the total of all the others added together. They infect all types and sizes of cellular life including animals, plants bacteria and fungi. Viruses are considered by some microbiologists to be a life form because they contain and carry genetic material, reproduce, and undergo alterations and changes to their composition and characteristics along lines similar to the concept of natural selection, although they lack key characteristics such as cell structures that are generally considered necessary in any entity for it to be defined as a ‘life form’. Because they possess some but not all of these attributes and properties, viruses have been described as ‘organisms at the edge of life’. In a previous Getting Technical article there was reference to a report in the Star newspaper that the existence of the smallest sub-nuclear particle, until then proposed in theory under the name of the ‘Higgs Boson’, had recently been proven in an experiment at the CERN complex in Europe. The mass of the Higgs Boson tends to zero so it is regarded as representing a state of transition between energy and mass or, in other words, ‘an entity at edge of mass’ which could be viewed as analogous to a virus being ‘at the edge of life’. Viruses are smaller and simpler than bacteria. By themselves they are inert and as such are not alive. They are just wherever University of Pennsylvania they are and not doing anything or reacting with any other entities or substances. However, when they come into contact with any suitable type of host they tend to ‘spring into life’ by hijacking genetic substances inside host cells and combining with these substances in ways which allow the viruses to reproduce themselves rapidly. As already mentioned, viruses are small. In general, viruses are about one hundredth of the average size of bacteria, which measure out at approximately one micron. At a hundred times smaller, viruses are therefore approximately one hundredth of one millionth of a metre – which explains why viruses are not visible under conventional optical microscopes. It was not until the first electron microscopes became operational during the early 1940s that the first visual images of viruses were able to be observed. Figure 1: Electron microphotograph of multiple bacteriophages attached to the wall of a bacterial cell. The caption on Figure 1 above refers to the viruses attached to the bacterial cell wall as ‘bacteriophages’. This is a typical example of technical nomenclature used in microbiology which can get very complex and confusing. Bacteriophages are types of viruses which almost exclusively attack only specific species of bacterial cells. To avoid using too many technical terms in this article, all viral types will come under the term ‘virus’. www.hvacronline.co.za RACA Journal I August 2020 37