QYR Market Research CRISPR And CRISPR-Associated (Cas) Genes Market | Page 3
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• Clustered regularly interspaced short palindromic repeats (CRISPR) are segments of
prokaryotic DNA containing short repetitions of base sequences. Each repetition is
followed by short segments of "spacer DNA" from previous exposures to a
bacteriophage virus or plasmid.
• The CRISPR/Cas system is a prokaryotic immune system that confers resistance to
foreign genetic elements such as those present within plasmids and phages, and
provides a form of acquired immunity. CRISPR associated proteins (Cas) use the
CRISPR spacers to recognize and cut these exogenous genetic elements in a manner
analogous to RNA interference in eukaryotic organisms. CRISPRs are found in
approximately 40% of sequenced bacterial genomes and 90% of sequenced archaea.
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