Q: Magazine Issue 9 Feb. 2022 | Page 10

COVID-19 NEWS
PEI-NI JONE , MD
Director of 3D Echocardiography , Director of Kawasaki Disease Clinic , Director of Quality in Echocardiography , Children ’ s Hospital Colorado
Professor , Pediatrics-Cardiology , University of Colorado School of Medicine
CHRISTINA OSBORNE , MD
Fellow , Critical Care , Children ’ s Hospital Colorado
Clinical Instructor , Pediatrics , University of Colorado School of Medicine

The Case for Two

Would kids diagnosed with MIS-C do better with more aggressive treatment up front ?
SAMUEL DOMINGUEZ , MD , PHD
Pediatric Infectious Diseases , Children ’ s Hospital Colorado
Professor , Pediatrics- Infectious Diseases , Course Director , Microbiology , Rounds Leader , Global Health and Disaster Course , University of Colorado School of Medicine
More than 50 years after Kawasaki disease was first described , nobody knows quite what causes it or why it happens in previously healthy children . The same is true of multi-inflammatory syndrome in children , or MIS-C , which investigators linked to SARS-CoV-2 infection in early 2020 . It was clear right away the two conditions had a lot in common , and so it made sense to treat them in much the same way . But Kawasaki disease experts like pediatric cardiologist Pei-Ni Jone , MD , and pediatric infectious disease specialist Samuel Dominguez , MD , quickly noticed a key difference : kids with MIS-C were sicker .
10 | CHILDREN ’ S HOSPITAL COLORADO