CONTENTS
It starts with a
A letter from a fellow questioner at Children ’ s Hospital Colorado
Dear colleagues ,
As medical researchers , we confront two gaps in the journey from the bench to the bedside : one sits between lab experiments to clinical trials . The other , just as wide , is the leap from trials to everyday practice . Only 14 % of the evidence we collect in clinical trials gets translated to actual patients .
Nowhere is that reality more apparent than in immunization delivery . The rate of uptake for the HPV vaccine , for example , is only 50 % among eligible patients . ( You can read more about the work we ’ re doing around vaccine hesitancy on page 8 of this issue ).
And as we weather the tail of this devastating pandemic , we know that a substantial percentage of people newly eligible to receive a vaccine don ’ t intend to take it . This is profoundly disheartening news . Not only do the available vaccines offer excellent protection against disease , but their widespread use stands to protect populations still vulnerable — such as children at risk for complications of COVID-19 .
In my field , implementation science , we know it ’ s not enough to operate from the top down — no matter how transformative the treatment might be . The pandemic delivers this lesson loud and clear . We need to work directly with the communities we serve to understand what ’ s working and what ’ s not .
Here on the Anschutz Medical Campus , I direct a joint effort between Children ’ s Hospital Colorado and the University of Colorado School of Medicine called the Adult and Child Consortium for Health Outcomes Research and Delivery Science , or ACCORDS . Our focus is on getting new treatments where they need to go . Some of this program ’ s offerings are practical : core support in study design , methodology , biostatistics . Others are forward thinking : mentorship for our next generation of caretaker-scientists and the development of innovative , cross-cutting implementation techniques .
We still have much to learn , not just about the human body , but about the human ways we interact . As providers , we sometimes have a complicated relationship with our patients . That ’ s particularly true in pediatrics . It ’ s one thing to trust a provider with your own health . It ’ s another to trust them with the health of your children .
Contents
FEATURE
12
PEDIATRICS
The Best Medicine
COVID-19 NEWS
8
Validating Vaccines
10
COVID Collab
11
NEONATOLOGY
How Does COVID-19 Present in Neonates ?
11
PEDIATRICS
Priority Information
SHORT ANSWER
3
CARDIOLOGY
A Proud Few
3
COLORECTAL AND UROGENITAL CARE
Pulling it Off
6
NEUROLOGY
A Focused Approach
BRIEFS
4
PULMONOLOGY
A More Effective Channel
4
SURGICAL ONCOLOGY
Keep in Training
6
MATERNAL FETAL MEDICINE
Upside-Down Ablation
15
NEUROLOGY
A Second Spin
16
CELLULAR THERAPY
Beyond the Fringe
ACCOLADES
19
A (:) List
I ’ ll keep doing all I can to earn that trust . I hope you will too .
Respectfully ,
ALLISON KEMPE , MD , MPH
Director , ACCORDS , Anschutz Medical Campus Ergen Family Endowed Chair in Pediatric Outcomes Research , Children ’ s Hospital Colorado
Professor of pediatrics , Division of General Academic Pediatrics , University of Colorado School of Medicine
2 | CHILDREN ’ S HOSPITAL COLORADO
For a digital version of this publication visit : childrenscolorado . org / Qmagazine
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