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PROTAC( Proteolysis Targeting chimera) platform of ARVINAS pharmaceutical
7. Targeting Xtandi and Zytiga Non Responder and Resistant population
About Us:
‣ Causes of resistance-Emerging mechanisms of Resistance to Xtandi / Zytiga
‣ How do the Mechanism of resistance to the Zytiga and Xtandi differ and do some of them overlap?
‣ Can AR-V7 splice biomarker be used to determine whether Xtandi and Zytiga will work??
‣ What other studies are looking at different ways to overcome resistance??
‣ Who will win the race for AR-V7 variant mCRPC??
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